Personal profile
Research interests
I am involved in clinical research in breast cancer including clinical trials focused on all stages of disease. Much of my research involved incorporating state-of-the-art imaging methods into clinical trials involving novel therapies and companion circulating and tissue biomarkers. Current interests include biomarker discovery including the use of functional imaging for predicting breast cancer risk and response to antitumor therapies. My work also focuses on understanding the tumor microenvironment and characterizing circulating biomarkers for disease prognosis and targeted therapies.
Current Research Focus:
• Role of non-steroidal anti-inflammatory drugs (NSAIDs) in breast cancer prevention
• Improving clinical outcomes and our understanding of immunotherapy approaches in breast cancer
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Collaborations and top research areas from the last five years
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BioNTech SE: A Phase I/II, multi-site, open-label, two-part trial to evaluate the efficacy, safety, and pharmacokinetics of BNT323 in combination with BNT327 in participants with advanced breast cancer
Almanzar, L. (CoI), Andrzejczyk, A. (CoI), Baer, L. (CoI), Cohen, J. (CoI) & Stopeck, A. (CoI)
04/29/26 → 01/17/27
Project: Research
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Biostar: BG01-2402: A Pivotal Phase II Clinical Trial of Utidelone Injection (UTD1) Plus Capecitabine (CAP) in HER2- negative Breast Cancer Patients with Brain Metastases
Andrzejczyk, A. (CoI), Baer, L. (CoI), Cohen, J. (CoI) & Stopeck, A. (CoI)
04/10/26 → 12/5/26
Project: Research
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ICON: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined...
Andrzejczyk, A. (CoI), Baer, L. (CoI), Cohen, J. (CoI) & Stopeck, A. (CoI)
02/27/26 → 10/3/26
Project: Research
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Overcoming Ganetespib Resistance to Combat Refractory HER2+ Breast Cancer
Alexandrova, E. (PI), Haley, J. (CoPI), Stopeck, A. (CoPI) & Li, J. (CoPI)
01/1/23 → 12/31/26
Project: Research
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MonarchE: A Randomized Open-Label Phase 3 Study of Abemaciclib Combined with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone in Patients with High Risk Node Positive Early Stage Hormone Receptor Positive
Baer, L. (CoI), Cohen, J. (CoI) & Stopeck, A. (CoI)
11/7/17 → 07/31/26
Project: Research
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Tucatinib and trastuzumab emtansine for patients with previously treated HER2-positive locally advanced and metastatic breast cancer: primary analysis of the randomized phase III trial HER2CLIMB-02☆
HER2CLIMB-02 study investigators, Mar 2026, In: Annals of Oncology. 37, 3, p. 341-352 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Concurrent water T2 and fat fraction mapping of the breast using the radial gradient and spin echo (RADGRASE) pulse sequence
Hagio, T., Galons, J. P., Roe, D., Marron, M. T., Thomson, C., Thompson, P., Stopeck, A. T., Bilgin, A., Altbach, M. I. & Chiang, J. T. A., May 2025, In: Magnetic Resonance Imaging. 118, 110355.Research output: Contribution to journal › Article › peer-review
Open Access -
Factors associated with avoidable 30-day readmissions in patients with cancer: a single institution study
Raiss, M. E., Mehta, K. K., Zhang, X., Kabacinski, A., Martorana, D., Mischo, J., Stopeck, A. & La Torre, G. N., Mar 2025, In: Supportive Care in Cancer. 33, 3, 206.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Metastatic breast cancer through the Oncotype DX Breast Recurrence Score®: insights from a small cohort study
Gemmill, J. A. L., Thompson, P., Batiste, R., Vacchi-Suzzi, C., Preece, C., Cohen, J., Baer, L., Mies, C., Turner, M., Russell, C. A. & Stopeck, A., Jul 2025, In: Breast Cancer Research and Treatment. 212, 2, p. 407-413 7 p.Research output: Contribution to journal › Article › peer-review
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Phase 2 trial of imprime and pembrolizumab immunotherapy in metastatic triple negative breast cancer patients who have progressed beyond first line chemotherapy
Stopeck, A. T., Abu-Khalaf, M., Borges, V., Chmielowski, B., Rao, R., Xie, B., Dudek, A. Z., Mina, L., O’Shaughnessy, J., Chisamore, M., Mattson, P., Gargano, M., Cox, J., Osterwalder, B., Drees, J., Harrison, B., Chan, A. S. H., Qiu, X., Ottoson, N. & Bose, N. & 3 others, , Jul 2025, In: Journal of Immunology. 214, 7, p. 1529-1538 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations