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Danny Bluestein

    1992 …2026

    Research activity per year

    Personal profile

    Research interests

    The focus of the Biofluids Research Group is the study of the dynamics of blood flow and cellular transport in the cardiovascular system, with an emphasis on flow-induced mechanisms underlying cardiovascular disease processes and their progression. Pathological flow fields that arise as a result of cardiovascular diseases or prosthetic devices have a complex interaction with blood vessels and blood itself. Over the last decade, evidence has accumulated indicating that local flow-induced stresses alter the molecular mechanisms of the formed elements of blood, and have a major effect on blood clotting. The end result can be thrombus formation that can occlude arteries, or handicap the functionality of implanted devices such as ventricular assist devices (VADs), total artificial hearts (TAH), and prosthetic heart valves.

     

    Biography

    Danny Bluestein, Ph.D. is a SUNY Distinguished Professor- a Professor of Biomedical Engineering at Stony Brook University, NY. He received his bachelor degree in Aeronautical Engineering from the Technion, Israel Institute of Technology, and Ph.D. in biomedical Engineering at Tel Aviv University, Israel. His research interests include the elucidation of physical forces that regulate cellular function in flowing blood, and translation of this knowledge to numerical and experimental strategies aimed at improving the design of blood recirculating devices such as prosthetic heart valves, ventricular assist devices and the total artificial heart, developing multiscale modeling approaches to describe blood clotting, and enhancing clinical diagnostics of cardiovascular diseases by using patient based numerical simulations. He has published 160 peer reviewed papers and book chapters. He served as an associate editor of the ASME Journal of Medical Devices and currently as associate editor of Frontiers Bioengineering, and of Bioengineering J. He is a member of the editorial board and an associate editor in leading bioengineering journals. He is an active member in the Biomedical Engineering Society, Bioengineering Division of the American Society for Mechanical Engineers where he served as the elected chair of the BED Biofluids technical committee. He is a member of the National Institutes of Health (NIH) Steering Committee of the Multiscale Modeling (MSM) Consortium, the Dassault Systèmes Simulia Living Heart Project, and the International Hemodynamic Society. Prof. Bluestein has received several major honors and awards including the Established Investigator Award from the American Heart Association (AHA) and the Quantum award from the NIH-NIBIB. He was elected as a Fellow of the Biomedical Engineering Society (BMES), a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), and a member of the National Academy of Inventors. He is the recipient of the 2021 ASME Savio L-Y Woo Translational Biomechanics Medal. He collaborates with several medical devices corporations and with leading CFD/FEA companies, and founded the Polynova Cardiovascular Inc. startup company. His research has been sponsored by various federal agencies and private foundations including the National Institutes of Health, the National Science Foundation, and the American Heart Association.

     

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