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Edwin Pratt

    20162026

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    • A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

      Zhang, Z., Ho, Y. J., Fang, X., Kim, M., Li, M., Luan, W., Hinterleitner, C., Haubner, S., Kogel, F., Pratt, E. C., Ozcelik, E., Reyes, J., Jiang, Q., Yang, V. W., Chen, Y. J., Wang, T., Liu, H., Hu, H., Zhuang, X. & Park, J. & 48 others, Paffenholz, S. V., Chen, K., Chang, Q., Kulick, A., Zhang, J., Chan, E., Rosiek, E., Fan, N., Williams, R. A., Wang, A. C., Freeman, S., Tian, S., Gunset, G., Garcia Angus, A., Lecomte, N., Yildirim, S. Y., Ali, E., Wu, M., Miranda, I. C., Antonescu, C. R., Basturk, O., Tarcan, Z., Rekhtman, N., Wilson, C., Basar, M., Sauter, J. L., Al-Ahmadie, H. A., Singer, S., Iacobuzio-Donahue, C., Rudin, C., de Stanchina, E., Ganesh, K., Romesser, P. B., Weigelt, B., Huh, D. D., Leibold, J., Feucht, J., Vázquez-García, I., Bott, M. J., Zamarin, D., Shah, S. P., Lewis, J. S., Amor, C., Pe’er, D., Mansilla-Soto, J., Filliol, A., Sadelain, M. & Lowe, S. W., May 14 2026, In: Cell. 189, 10, p. 2898-2917.e42

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • A tissue-informed deep learning-based method for positron range correction in preclinical Ga PET imaging

      Encina-Baranda, N., Paneque-Yunta, R. J., Lopez-Rodriguez, J., Pratt, E. C., Nguyen, T. N., Grimm, J., Lopez-Montes, A. & Herraiz, J. L., Dec 2026, In: EJNMMI Physics. 13, 1, 66.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Minimal chemical modification enables alpha/beta radiolabeling of sacituzumab govitecan for targeted therapy in high grade serous ovarian cancer

      Loor, A., Mack, K. N., Bauer, D., Ingham, A., Pratt, E. C. & Lewis, J. S., Jun 2026, In: European Journal of Nuclear Medicine and Molecular Imaging. 53, 7, p. 4587-4596 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Trop-2.2–Directed Radioimmunotherapy with177Lu,225Ac, and212Pb in a Pancreatic Cancer Model

      Pratt, E. C., Bauer, D., Carter, L. M., Cornejo, M., Carrasco, S. E., Kaminsky, S., de Gregorio, R., Loor, A., Friedl, O., Bolaender, A., Chao, G., Castanares, M. A., Collins, E. C. & Lewis, J. S., Apr 15 2026, In: Clinical Cancer Research. 32, 8, p. 1462-1474 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • ImmunoPET for mesothelin positive tissues using bio-orthogonal in-vivo click chemistry

      Pratt, E. C., Mandleywala, K., Bauer, D., Bolaender, A., Chao, G., Castanares, M. A., Collins, E. C. & Lewis, J. S., Sep 1 2025, In: Nuclear Medicine and Biology. 148-149, 109051.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
    View all 24 Research outputs