Personal profile
Research interests
My research integrates developmental psychopathology with neuroscience to identify novel strategies for prevention and treatment of psychiatric disorders. This integrative approach has led me utilize diverse methods in my research to test research hypotheses, including structural and functional magnetic resonance imaging (MRI), neuromelanin-sensitive MRI, event-related potentials, multi-dimensional behavioral phenotypes, and longitudinal and genetically informed study designs.
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Collaborations and top research areas from the last five years
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A Randomized Double-Blind Placebo-Controlled Parallel-Group Study to Evaluate the Efficacy Safety and Tolerability of Luvadaxistat in Subjects With Cognitive Impairment Associated With Schizophrenia
Gil, R. (PI) & Perlman, G. (CoPI)
Neurocrine Biosciences Incorporated
08/17/24 → 08/16/26
Project: Research
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Elucidating Cholinergic Relationships with Psychosis And Cognitive Deficits in Schizophrenia
Weinstein, J. (PI), Abi-Dargham, A. (CoPI), Gil, R. (CoPI), Moeller, S. (CoPI), Perlman, G. (CoPI), Slifstein, M. (CoPI) & Van Snellenberg, J. (CoPI)
National Institute of Mental Health
07/1/24 → 02/28/27
Project: Research
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Developmental Pathways Model of Depression Heterogeneity
Kotov, R. (PI), Abi-Dargham, A. (CoPI), Klein, D. (CoPI), Kuan, P. F. (CoPI), Nelson, B. (CoPI) & Perlman, G. (CoPI)
National Institute of Mental Health
05/22/24 → 02/28/27
Project: Research
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Neuromelanin MRI: A Tool for Non-Invasive Investigation of Dopaminergic Abnormalities in Adolescent Substance Use
Perlman, G. (PI), Abi-Dargham, A. (CoPI), Kotov, R. (CoPI), Moeller, S. (CoPI) & Van Snellenberg, J. (CoPI)
National Institute on Drug Abuse
09/15/23 → 06/30/26
Project: Research
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Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
Abi-Dargham, A. (PI), Moeller, S. (CoPI), Perlman, G. (CoPI), Schwartz, J. (CoPI), Slifstein, M. (CoPI), Van Snellenberg, J. (CoPI) & Weinstein, J. (CoPI)
National Institute on Drug Abuse
09/30/22 → 08/31/25
Project: Research
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A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial
Fonteneau, C., Tamayo, Z., Price, A., Pan, L., Afriyie-Agyemang, Y., Agrawal, S., Butler, A., Cail, C., Calkins, M., Chakilam, A. R., Forselius-Bielen, K., Fram, G., Frazier, A., Gil, R., Govil, P., Gray, D. L., Grinband, J., Gur, R. C., Haubold, N. K. & Heffernan, Z. & 24 others, , Mar 2026, In: Journal of Psychiatric Research. 194, p. 196-210 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Prospective prediction of first-onset generalized and social anxiety disorders in adolescent girls
Liu, J., Yao, N., Perlman, G., Klein, D. N., Kotov, R. & Mu, W., Jun 2026, In: Journal of Anxiety Disorders. 120, 103153.Research output: Contribution to journal › Article › peer-review
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Auditory and Visual Thalamocortical Connectivity Alterations in Unmedicated People With Schizophrenia: An Individualized Sensory Thalamic Localization and Resting-State Functional Connectivity Study
Williams, J. C., Tubiolo, P. N., Gil, R. B., Zheng, Z. J., Silver-Frankel, E. B., Haubold, N. K., Abeykoon, S. K., Pham, D. T., Ojeil, N., Bobchin, K., Slifstein, M., Weinstein, J. J., Perlman, G., Horga, G., Abi-Dargham, A. & Van Snellenberg, J. X., Dec 2025, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 10, 12, p. 1239-1248 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cholinergic tone abnormalities and relationships with smoking severity in human cigarette smokers: exploratory positron emission tomography study using [18F]VAT
Moeller, S. J., Weinstein, J. J., Varnas, B., Orellano, O., Gil, R., Perlman, G., Abeykoon, S., Meng, J., Oprea, I., Hu, B., Qu, W., Slifstein, M. & Abi-Dargham, A., Sep 2025, In: Molecular Psychiatry. 30, 9, p. 4064-4071 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Do Predictors of First-Onset Depression Differ Between Youth with and without Anxiety Disorders?
Grieshaber, A., Perlman, G., Kotov, R. & Klein, D. N., 2025, (Accepted/In press) In: Journal of Clinical Child and Adolescent Psychology.Research output: Contribution to journal › Article › peer-review
1 Scopus citations