Grants & Projects per year
Personal profile
Research interests
Our research falls into four broad areas:
(1) Elucidating the molecular interactions that govern proliferation and differentiation of neural stem cells and progenitors.
(2)Developing animal models for human neurological disorders including Autism, Parkinson’s and epilepsy.
(3)Pioneering technologies to engineer chromosomes and modulate gene expression.
(4) Determining the neurodevelopmental consequences of environmental pollutants including PFAS "forever chemicals".
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Towards Personalized Treatments for ASD
Sirotkin, H. I. (PI) & Wollmuth, L. (CoPI)
03/6/26 → 03/5/27
Project: Research
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Defining the neurotoxic and neurodevelopmental health risks of per-and polyfluoroalkyl substances
Sirotkin, H. I. (CoI), Atilla-Gokcumen, G. (PI) & Aga, D. (CoI)
National Inst of Environmental Health Sciences
01/13/25 → 10/31/29
Project: Research
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Novel functions for NMDARs in neural crest development
Sirotkin, H. I. (PI)
Eunice Kennedy Shriver National Institute of Child Health & Human Dev
09/6/23 → 08/31/26
Project: Research
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Research Seed Grant Program
Agrawal, S. (CoI), Boon, E. (CoI), Chakraborty, N. (CoI), Chen, J. (CoI), Citovsky, V. (CoI), Feinberg, E. (CoI), Fries, B. (CoI), Hamideh, S. (CoI), Henkes, G. A. (CoI), Talos, F. M. (CoI), Kim, H. (CoI), Leung, H.-C. (CoI), Mofakham, S. (CoI), Mueller, K. (CoI), Pisconti, D. (CoI), Salman, E. (CoI), Shelly, M. (CoI), Sirotkin, H. I. (CoI), Almas, B. (PI), Iacabucci, J. (PI), Aga, D. (CoI), Alexander, J. (CoI), Atilla-Gokcumen, G. (CoI), Beverley, J. (CoI), Boivin, B. (CoI), Brooks, T. (CoI), Callahan, B. (CoI), Cavuoto, L. (CoI), Chen, H.-Y. (CoI), Choi, S. (CoI), Cook, T. (CoI), Downs, C. (CoI), Elias Arriaga, A. L. (CoI), Faghihi, D. (CoI), Feldblyum, J. (CoI), Ferkey, D. (CoI), Ford Versypt, A. (CoI), Gokcumen, O. (CoI), Guo, H. (CoI), Halterman, M. (CoI), Halterman, M. (CoI), Huang, R. (CoI), Jarvis, J. (CoI), Ke, C. (CoI), Lacy, D. (CoI), Lao, Y.-H. S. (CoI), Lapenis, A. (CoI), Lee, J. U. (CoI), Leighton, G. (CoI), Liu, H. (CoI), Liu, X. (CoI), Loh, S. (CoI), Luo, J. (CoI), Meyer, P. (CoI), Ning, F. (CoI), Oktyabrsky, S. (CoI), Orom, H. (CoI), Park, J. (CoI), Paul, M. (CoI), Razavi Aghjeh, M. J. (CoI), Scimemi, A. (CoI), Shin, D. (CoI), Shin, S. (CoI), Siegel, P. (CoI), Sisto, S. A. (CoI), Smith, B. (CoI), Subryan, H. (CoI), Sun, Y. (CoI), Tripp, J. (CoI), Tumey, L. N. (CoI), Wang, Y. (CoI), Watson, D. (CoI), Xu, W. (CoI) & Zhou, C. (CoI)
04/1/22 → 03/31/27
Project: Research
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Thomas Hartman Center for Parkinson's Research
Fontanini, A. (PI), Bowen, M. E. (CoI), Collins III, W. (CoI), Colognato, H. (CoI), Hu, C.-K. (CoI), Kritzer, M. (CoI), Lamberg, E. M. (CoI), Leung, H.-C. (CoI), Maffei, A. (CoI), Maurer, C. (CoI), Muratori, L. M. (CoI), Neiman, A. (CoI), Plotkin, J. (CoI), Puopolo, M. (CoI), Riessland, M. (CoI), Schwartz, G. (CoI), Shelly, M. (CoI), Sher, R. (CoI), Shrestha, P. (CoI), Sirotkin, H. I. (CoI), Solomon, I. C. (CoI), Thomsen IV, G. H. (CoI), Wollmuth, L. (CoI), Wu, S. (CoI), Xiong, Q. (CoI), Role, L. (PI), Christodoulou, C. (CoI), Evinger, L. (CoI), Halegoua, S. (CoI), Huang, C. (CoI), Levine, J. (CoI), Lutterbie, J. (CoI), Manganas, L. (CoI), Matthews, G. (CoI), Park, I. M. (CoI) & Talmage, D. (CoI)
04/15/13 → 07/31/27
Project: Research
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Conservation of human NMDA receptor subunits and disease variants in zebrafish
Nebet, E. R., Aprea, C., Zoodsma, J. D., Raab, W. J., Sirotkin, H. I. & Wollmuth, L. P., Dec 2025, In: BMC Genomics. 26, 1, 1042.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Optimizing Prime Editing in Zebrafish
Basharat, R., Rizzo, G., Zoodsma, J. D., Wollmuth, L. P. & Sirotkin, H. I., 2025, (Accepted/In press) In: CRISPR Journal.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Synthesis and Evaluation of Cationic Porphyrin-Based Organic Nanocages for the Removal of 38 PFAS from Water: Experimental, Theoretical, and Eco-toxicological Insights
Sanchez-Lievanos, K. R., Zhang, D., Simpson, S. M., Wijayahena, M. K., Rizzo, G., Aguilar, J. M. N., Abaya, L. M., Dovi, J. M., Sirotkin, H. I., Crawley, M. R., Cook, T. R. & Aga, D. S., Mar 14 2025, In: ACS ES and T Engineering. 5, 3, p. 701-713 13 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Behavioral Assays Dissecting NMDA Receptor Function in Zebrafish
Zoodsma, J. D., Gomes, C. I., Sirotkin, H. I. & Wollmuth, L. P., 2024, Methods in Molecular Biology. Humana Press Inc., p. 243-255 13 p. (Methods in Molecular Biology; vol. 2799).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Scopus citations -
Developmental loss of NMDA receptors results in supernumerary forebrain neurons through delayed maturation of transit-amplifying neuroblasts
Napoli, A. J., Laderwager, S., Zoodsma, J. D., Biju, B., Mucollari, O., Schubel, S. K., Aprea, C., Sayed, A., Morgan, K., Napoli, A., Flanagan, S., Wollmuth, L. P. & Sirotkin, H. I., Dec 2024, In: Scientific Reports. 14, 1, 3395.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations