Grants & Projects per year
Personal profile
Research interests
- Habit learning
- Neurological disorders
- Obsessive compulsive disorder
- Basal ganglia
- Striatum
- Synaptic plasticity
- 2-photon laser scanning microscopy, electrophysiology
- Optogenetics
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Dive into the research topics where Josh Plotkin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Disrupted Striatal Cholinergic Signaling and Compulsive Motor Behaviors
Plotkin, J. (PI)
National Inst of Neurological Disorders & Stroke
09/1/26 → 08/31/27
Project: Research
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Thomas Hartman Center for Parkinson's Research
Fontanini, A. (PI), Bowen, M. E. (CoI), Collins III, W. (CoI), Colognato, H. (CoI), Hu, C.-K. (CoI), Kritzer, M. (CoI), Lamberg, E. M. (CoI), Leung, H. C. (CoI), Maffei, A. (CoI), Maurer, C. (CoI), Muratori, L. M. (CoI), Neiman, A. (CoI), Plotkin, J. (CoI), Puopolo, M. (CoI), Riessland, M. (CoI), Schwartz, G. (CoI), Shelly, M. (CoI), Sher, R. (CoI), Shrestha, P. (CoI), Sirotkin, H. I. (CoI), Solomon, I. C. (CoI), Thomsen IV, G. H. (CoI), Wollmuth, L. (CoI), Wu, S. (CoI), Xiong, Q. (CoI), Role, L. (PI), Christodoulou, C. (CoI), Evinger, L. (CoI), Halegoua, S. (CoI), Huang, C. (CoI), Levine, J. (CoI), Lutterbie, J. (CoI), Manganas, L. (CoI), Matthews, G. (CoI), Park, I. M. (CoI) & Talmage, D. (CoI)
04/15/13 → 08/31/27
Project: Research
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Exploratory study of the cholinergic system in Obsessive Compulsive Disorder (OCD)
Abi-Dargham, A. (PI), Plotkin, J. (CoPI), Slifstein, M. (CoPI) & Gil, R. (CoI)
National Institute of Mental Health
06/6/24 → 05/31/26
Project: Research
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Pathological Dendritic Engagement of Striatal Cholinergic Interneurons in Parkinsonian and Dyskinetic Mice
Plotkin, J. (PI)
US Israel Binational Science Foundation
10/1/22 → 09/30/26
Project: Research
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NRSA for Alexander Baez: Functional study of the role of SAPAP3 postsynaptic density protein on dorsolateral striatal cholinergic interneurons
Plotkin, J. (PI), Wollmuth, L. (CoPI) & Baez, A. (CoPI)
National Institute of Mental Health
09/2/22 → 09/1/26
Project: Research
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Age-related nigral downregulation of the Parkinson’s risk factor FAM49B primes human microglia for inflammaging
Martin, J., Lai, G. J., Park, C. Y., West, C., Van Brunt, T., Ahmed, S., Lawal, S., Dickson, M., Russo, T., Akmentin, W., Weiner, M., Hobel, Z. B., Kolisnyk, B., Plotkin, J. L., Troyanskaya, O. G. & Riessland, M., Dec 2026, In: npj Aging. 12, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Striatal cholinergic interneurons exhibit compartment-specific anatomical and functional organization in the mouse
Hobel, Z. B., Yang, L. T., Brechbill, T. R., Liu, Q., Goldberg, J. A. & Plotkin, J. L., Jan 6 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 1, e2519939123.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Synchronous activation of striatal cholinergic interneurons induces local serotonin release
Matityahu, L., Hobel, Z. B., Berkowitz, N., Malgady, J. M., Gilin, N., Plotkin, J. L. & Goldberg, J. A., Dec 2026, In: Nature Communications. 17, 1, 2278.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Editorial: Reviews in cellular neurophysiology 2022: neurophysiological mechanisms in the aging brain
Plotkin, J. L., Graves, S. M. & Riessland, M., 2024, In: Frontiers in Cellular Neuroscience. 18, 1385783.Research output: Contribution to journal › Editorial
Open Access1 Scopus citations -
Pathway-specific alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior
Malgady, J. M., Baez, A., Hobel, Z. B., Jimenez, K., Goldfried, J., Prager, E. M., Wilking, J. A., Zhang, Q., Feng, G. & Plotkin, J. L., Nov 28 2023, In: Cell Reports. 42, 11, 113384.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations