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Kehan Ren

    20162026

    Research activity per year

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    • Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment

      Chen, S., Barajas, S., Vemula, S., Yang, Y., Simpson, E., Gao, H., Li, R., Behzadnia, F., Nabinger, S. C., Schmitz, D. A., Chen, H., Cai, W., Xiao, S., Luo, R., Amin, M. A., Capitano, M. L., Ropa, J. P., Fahey, A., Zhou, S. & Mays, T. M. & 31 others, Sotelo, M., Pan, H., Hu, S. K., Veranga, S., Ali, M., Shumilina, M., Kapur, R., Ren, K., Jia, Y., Liu, H., Khan, I., Abaza, Y., Altman, J. K., Eklund, E. A., Godley, L. A., Zhang, C. R., Ji, P., Masters, S. L., Croker, B. A., Boswell, H. S., Sandusky, G. E., Gao, Z., Mayo, L. D., Savage, S. A., Halene, S., Dou, Y., Platanias, L. C., Sukhanova, M., Liu, Y., Abdel-Wahab, O. & Liu, Y., Feb 2 2026, In: Journal of Clinical Investigation. 136, 3, e184285.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations
    • Spatial transcriptomic analyses highlight distinct erythroid niches in mice and humans

      Han, X., Ren, K., Wang, P., Bi, H., Li, E., Aydemir, I., Ji, A., Cai, W., Soleimanisardoo, L., Wai, C. M., Schipma, M. J., Liu, Y., Goldstein, J., Sukhanova, M., Yang, J. & Ji, P., Jul 2026, In: Nature Genetics. 58, 7, p. 1620-1631 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
    • DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death

      Bi, H., Ren, K., Wang, P., Li, E., Han, X., Wang, W., Yang, J., Aydemir, I., Tao, K., Ma, R., Godley, L. A., Liu, Y., Shukla, V., Bartom, E. T., Tang, Y., Blanc, L., Sukhanova, M. & Ji, P., Dec 2025, In: Nature Communications. 16, 1, 7195.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations
    • Development of iPSC-derived human bone marrow organoid for autonomous hematopoiesis and patient-derived HSPC engraftment

      Ren, K., Li, E., Aydemir, I., Liu, Y., Han, X., Bi, H., Wang, P., Tao, K., Ji, A., Chen, Y. H., Yang, J., Sukhanova, M. & Ji, P., Jan 14 2025, In: Blood Advances. 9, 1, p. 54-65 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      32 Scopus citations
    • Overall cancer risk in people with deleterious germline DDX41 variants

      Korotev, S. C., Cheng, J. X., Haribabu, Y., Strauss, J., Dominguez, S., Koppayi, A., Perpich, M., Pies, M., Moma, L., Kim, A., Basdag, H., Rodgers, C., Kosuri, S., Saiki, R., Makishima, H., Tawde, S., Galasinski, S., Kandikatla, P., Subramanian, H. P. & Ren, K. & 7 others, Bi, H., Mohammadhosseini, M., Ogawa, S., Ji, P., Agarwal, A., Das, S. & Godley, L. A., Feb 13 2025, In: Haematologica. 110, 9, p. 2076-2090 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations