Grants & Projects per year
Personal profile
Research interests
Our fundamental goal is to understand how intracellular components, ranging from molecules to organelles, organize across cells to be in the right place, at the right time.
We focus on dividing eukaryotic cells, in which membrane bound compartments and cytoskeletal networks undergo significant restructuring. To gain insight on organization in this cellular context, we combine molecular and cell biological approaches with quantitative, optical microscopy.
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Collaborations and top research areas from the last five years
Grants & Projects
- 1 Active
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SBF Funds to fund 10 Seed Grants Advancing AI Research/Diffusion
Varshney, L. (PI), Carlini, L. (CoI), Choi, H. (CoI), Dave, A. (CoI), Enikolopov, G. (CoI), Klein, D. N. (CoI), Li, J. (CoI), Ma, T. (CoI), Miranda, V. (CoI), Samaras, D. (CoI), Sirotkin, H. I. (CoI), Sunar, U. (CoI), Vitek, N. (CoI), Yin, Z. (CoI), Jeon, M. E. (CoI) & Weiss, S. (CoI)
08/1/26 → 07/31/27
Project: Research
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Spastin regulates anaphase chromosome separation distance and microtubule-containing nuclear tunnels
Kelley, M. E., Carlini, L., Kornakov, N., Aher, A., Khodjakov, A. & Kapoor, T. M., Apr 1 2024, In: Molecular Biology of the Cell. 35, 4, ar48.Research output: Contribution to journal › Article › peer-review
Open Access -
Coupling of microtubule bundles isolates them from local disruptions to set the structural stability of the anaphase spindle
Carlini, L., Renda, F., Pamula, M. C., Khodjakov, A. & Kapoor, T. M., Sep 27 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 39, e2204068119.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells
Renda, F., Miles, C., Tikhonenko, I., Fisher, R., Carlini, L., Kapoor, T. M., Mogilner, A. & Khodjakov, A., Mar 14 2022, In: Current Biology. 32, 5, p. 1049-1063.e4Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial membrane tension governs fission
Mahecic, D., Carlini, L., Kleele, T., Colom, A., Goujon, A., Matile, S., Roux, A. & Manley, S., Apr 13 2021, In: Cell Reports. 35, 2, 108947.Research output: Contribution to journal › Article › peer-review
Open Access -
Microtubules Enhance Mesoscale Effective Diffusivity in the Crowded Metaphase Cytoplasm
Carlini, L., Brittingham, G. P., Holt, L. J. & Kapoor, T. M., Sep 14 2020, In: Developmental Cell. 54, 5, p. 574-582.e4Research output: Contribution to journal › Article › peer-review
Open Access