Grants & Projects per year
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Research interests
With the increasing number of immunodeficient subjects and the increase of the lifespan of these subjects due to the advance in medicine there has been a concomitant rise in the number of cases of life-threatening fungal infections. Current antifungal treatments are often inadequate due a tardy diagnosis, collateral effects, and drug resistance. Dr. Del Poeta’s research team studies sphingolipid metabolism and signaling in fungal and mammalian cells to identify new markers for early diagnosis and specific microbial enzymes/molecules essential to cause infection in the attempt to develop new antifungal targets.
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Collaborations and top research areas from the last five years
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New Antifungals Targeting the Synthesis of Fungal Sphingolipids
Del Poeta, M. (PI) & Ojima, I. (CoPI)
National Institute of Allergy & Infectious Disease
07/1/26 → 06/30/27
Project: Research
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IPA Agreement to Provide Salary Support for Deveney Dasilva
Del Poeta, M. (PI)
Veterans Administration Medical Ctr at Northport
10/6/25 → 10/6/27
Project: Research
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Developing New Antifungals Against Sterolglycosidases
Del Poeta, M. (PI), Airola, M. V. (CoPI), Ojima, I. (CoPI) & Rizzo, R. C. (CoPI)
National Institute of Allergy & Infectious Disease
06/12/25 → 05/31/27
Project: Research
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VA Assignment to provide salary support for Vanessa Karina Kolasinski
Del Poeta, M. (PI)
Veterans Administration Medical Ctr at Northport
05/12/25 → 05/12/27
Project: Research
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Sphingosine Kinase and Cryptococcal Granuloma
Del Poeta, M. (PI), Airola, M. V. (CoPI), Luberto, C. (CoPI), Ojima, I. (CoPI), Rizzo, R. C. (CoPI) & Sheridan, B. (CoPI)
National Institute of Allergy & Infectious Disease
02/1/25 → 01/31/27
Project: Research
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MoCox6 is a regulator of mitophagy and a druggable target in Magnaporthe oryzae
Wu, M. H., Lv, Y. N., Li, H., Qian, H., Wei, Y. Y., Zhang, Y. R., Liang, S., Zhu, X. M., Lu, J. P., Del Poeta, M., Wang, Z. H., Lee, Y. H., Naqvi, N. I., Wilson, R. A., Klionsky, D. J., Lin, F. C. & Liu, X. H., Jun 2026, In: Nature Microbiology. 11, 6, p. 1662-1676 15 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Phosphatidylcholine biosynthesis pathways in Cryptococcus neoformans: functional interplay and impact on virulence
Timboni, F. D. S., Garay, A. V., de Castro, R. J. A., Trindade, G. B., Silva, N. O. D., Coelho, L. C., Dias, V. M., de Sousa, A. P. C. V., Del Poeta, M., Albuquerque, P., Bocca, A. L. & Fernandes, L., 2026, In: Frontiers in Cellular and Infection Microbiology. 15, 1736171.Research output: Contribution to journal › Article › peer-review
Open Access -
Steryl glucosides as a novel chemosensitizer: Enhancing doxorubicin response in estrogen receptor-positive breast cancer
Cavalcanti-Neto, M. P., Brauer, V. S., Rella, A., Shamseddine, A., Dasilva, D., Matos, G. S., de Sa, N. P., Shroyer, K., Hannun, Y. & Del Poeta, M., Aug 2026, In: Biomedicine and Pharmacotherapy. 201, 119653.Research output: Contribution to journal › Article › peer-review
Open Access -
α-1,3-Glucan-Driven Remodeling of the Conidial Cell Wall in an Aspergillus fumigatus Vaccine Strain Alters Innate Immune Recognition
Singh, K., Ankur, A., Yarava, J. R., Fernandes, C. M., Vascelli, G., Sulla, A., Zelante, T., Del Poeta, M. & Wang, T., Apr 8 2026, In: Journal of the American Chemical Society. 148, 13, p. 14320-14332 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Celebrating the fifth edition of the International Symposium on Fungal Stress – ISFUS, a decade after its 2014 debut
Alder-Rangel, A., Rangel, A. E. A., Casadevall, A., Gusa, A., Xue, C., Boone, C. M., Hittinger, C. T., Masuda, C. A., Olivares-Yañez, C., Bell-Pedersen, D., Washington, E. J., Braus, G., Janbon, G., Pócsi, I., Stajich, J. E., Dunlap, J. C., Bennett, J. W., Heitman, J., Lu, L. & Landi, L. & 19 others, , Aug 2025, In: Fungal Biology. 129, 5, 101590.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations