Grants & Projects per year
Personal profile
Research interests
- Robotic and conventional surgery for colon and rectal cancer, familial polyposis, diverticulitis, Inflammatory bowel disease including Crohn’s disease and ulcerative colitis, and rectal prolapse
- Ileoanal J pouch creation and management
- Transanal surgery
- Treatment of anorectal abscess, fistula, fissure anal condyloma, hemorrhoids
- HPV related anal disease screening and management, including HRA(high resolution anoscopy)
- Colonoscopy
- Anorectal ultrasound
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Collaborations and top research areas from the last five years
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IL-17A-Mediated Regulation of Stromal and Epithelial Cell Interactions in the Intestine
Kumar, P. (PI), Biswas, P. (CoPI), Denoya, P. I. (CoPI) & Sheridan, B. (CoPI)
National Inst of Diabetes Digestive Kidney Disease
07/1/26 → 04/30/27
Project: Research
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A Safety and Effectiveness Prospective Blinded clinical study to validate xBar system as monitoring tool for anastomotic leaks detection
Nagle, D. (PI), Ahn, N. (CoPI), Denoya, P. I. (CoPI) & Yelika, S. (CoPI)
06/20/24 → 12/31/26
Project: Research
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SafeHeal Diverting Ileostomy Pivotal Study (SH-SOC23)
Nagle, D. (PI), Ahn, N. (CoPI), Denoya, P. I. (CoPI) & Yelika, S. (CoPI)
03/26/25 → 02/12/26
Project: Research
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CookMyosite: A Two-Stage, Randomized, Controlled Trial Comparing the Safety and Efficacy of Iltamiocel with Placebo in the Treatment of Female Participants with Chronic Fecal Incontinence and a History of Obstetric Anal Sphincter Injury
Nagle, D. (PI), Bergese, S. (CoPI), Denoya, P. I. (CoPI) & Budnick, L. E. (PI)
02/20/24 → 08/8/26
Project: Research
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TIGENIX: A Phase 111 Study of Cx601 Adult Allogeneic Expanded Adipose Derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula In Patients with Crohn's Disease ADMIRE CD Study
Monzur, F. (PI), Denoya, P. I. (CoPI), Nagle, D. (CoPI), Morganstern, B. (PI), Genua, J. (CoPI), Li, E. (CoPI) & LaComb, J. (CoI)
11/30/19 → 08/15/24
Project: Research
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IL-17RA signaling promotes the dedifferentiation of Paneth progenitors through ADAM17 to regenerate gut epithelium post-irradiation
Kempen, C. G., Singh, A., Breau, K. A., Tariq, H. I., Yu, Y., Gaudino, S. J., Bahadur, T., Orzechowska-Licari, E., Eskiocak, O., Shiomitsu, K., Blumberg, R., Denoya, P., Martin, R., Bialkowska, A. B., Beyaz, S., Magness, S. T., Hearing, P., Kim, H. K., Sheridan, B. S. & Dempsey, P. & 1 others, , Dec 2026, In: Nature Communications. 17, 1, 4091.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Who Should Undergo Drain Studies After Percutaneous Drainage in Complicated Diverticulitis?
Froehlich, M. H., Wady, H., Roy, I. V., Smithy, W. B., Yelika, S. B., Ahn, N. J., Denoya, P. I. & Nagle, D. A., Jul 2026, In: World Journal of Surgery. 50, 7, p. 1797-1806 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Multidisciplinary Postoperative Ileus Management: A Narrative Review
Yu, S., Kerolus, K., Jin, Z., Bajrami, S., Denoya, P. & Bergese, S. D., Aug 2025, In: Medicina (Lithuania). 61, 8, 1344.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
Trends in operative time and patient outcomes in robotic colostomy reversal: surgeons’ short-term pain for patients’ long-term gain
Froehlich, M. H., Van Roy, I., Krichmar, A., Mazis, C. M., Roberts, D. A., Yelika, S. B., Ahn, N. J., Denoya, P. I. & Nagle, D. A., 2025, (Accepted/In press) In: Surgical Endoscopy.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Erratum: IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation (Cell Reports (2024) 43(5), (S2211124724005345), (10.1016/j.celrep.2024.114206))
Singh, A., Beaupre, M., Villegas-Novoa, C., Shiomitsu, K., Gaudino, S. J., Tawch, S., Damle, R., Kempen, C., Choudhury, B., McAleer, J. P., Sheridan, B. S., Denoya, P., Blumberg, R. S., Hearing, P., Allbritton, N. L. & Kumar, P., Aug 27 2024, In: Cell Reports. 43, 8, 114643.Research output: Contribution to journal › Comment/debate
Open Access