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Research interests
Our research focuses on understanding the neural circuits and cellular mechanisms underlying voluntary motor control, particularly the role of glial cells—such as astrocytes—in modulating neuronal activity. We explore how astrocytes interact with neurons to regulate complex motor behaviors, with a special focus on circuits involved in speech production and respiratory control. By utilizing genetic, optical, and electrophysiological techniques, our research aims to dissect the contributions of specific cell types to motor circuit function. A significant aspect of our work addresses the neural basis of speech and its disorders, including developmental stuttering. By studying how astrocytes influence respiratory behaviors, we aim to uncover the mechanisms connecting breathing and speech, translating discoveries from bench to bedside and back.
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Collaborations and top research areas from the last five years
Grants & Projects
- 1 Active
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Start Up Funds from Stony Brook Foundation for Shahriar Shekhbahaei
Sheikhbahaei, S. (PI)
11/1/24 → 10/31/27
Project: Research
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Interdisciplinary Consensus Guidelines on Stuttering
Maguire, G. A., Duerr, H. A., SheikhBahaei, S., Kikuchi, Y., LaSalle, L., Valente, T. J., Bohnen, A. J., Santos, T. P., Leal, G., Binder, D., Alva, G. & Mattingly, G., Aug 2026, In: Psychiatric Times. 43, 8, p. 14-18 5 p.Research output: Contribution to journal › Article › peer-review
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Speech Motor Deficits in Developmental Stuttering and Parkinson's Disease: From Cellular and Circuit to Network-Level Disruptions
Turk, A., Millwater, M., Sheikh-Bahaei, S., Mollaei, F., Riessland, M. & SheikhBahaei, S., Feb 2026, In: European Journal of Neuroscience. 63, 3, e70393.Research output: Contribution to journal › Review article › peer-review
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Stuttering: Our Current Knowledge, Research Opportunities, and Ways to Address Critical Gaps
Chang, S. E., Below, J. E., Chow, H. M., Guenther, F. H., Hampton Wray, A. M., Jackson, E. S., Max, L., Neef, N. E., SheikhBahaei, S., Shekim, L., Tichenor, S. E., Walsh, B., Watkins, K. E., Yaruss, J. S. & Bernstein Ratner, N., 2025, In: Neurobiology of Language. 6Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
Brainstem astrocytes regulate breathing and may affect arousal state in rats
Bishop, M. & SheikhBahei, S., Mar 1 2024, In: Physiology and Behavior. 275, 114457.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Contributions of carotid bodies, retrotrapezoid nucleus neurons and preBötzinger complex astrocytes to the CO2-sensitive drive for breathing
SheikhBahaei, S., Marina, N., Rajani, V., Kasparov, S., Funk, G. D., Smith, J. C. & Gourine, A. V., Jan 1 2024, In: Journal of Physiology. 602, 1, p. 223-240 18 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations