Grants & Projects per year
Personal profile
Research interests
The goal of my lab is to examine the generation, integration and function of new neurons. We use molecular, cellular, in vitro / in vivo imaging, physiological and behavioral approaches to study where, when and how these new neurons integrate into the existing adult circuitry. Other than the mechanisms of integration, understanding the physiological function of these integrating/integrated neurons in the brain is another goal of the lab.
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Collaborations and top research areas from the last five years
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Activity-dependent astrocyte glucose dynamics regulate hippocampal neurogenesis
Ge, S. (PI) & Xiong, Q. (CoPI)
01/1/25 → 12/31/26
Project: Research
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Examine the Local Glucose Dynamics in Activity-Induced Hippocampal Neurogenesis
Ge, S. (PI) & Wang, X. (CoPI)
National Inst of Neurological Disorders & Stroke
09/20/22 → 08/31/24
Project: Research
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Dynamic Neurovascular Coupling in Activity-Induced Hippocampal Neurogenesis
Ge, S. (PI)
05/1/20 → 03/31/23
Project: Research
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Mechanistic study of declining hippocampal neurogenesis in the aging brain
Ge, S. (PI) & Xiong, Q. (CoPI)
05/1/20 → 01/31/26
Project: Research
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Astrocytic glucose metabolism regulates the survival of newborn hippocampal neurons in the adult brain
Wang, X., Chen, L., Kim, T. A., Wang, Z., Peng, X., Syty, M. D., Wang, F., Zhang, Y., Wehrle, P., Nasu, Y., Xiong, Q. & Ge, S., Aug 19 2026, In: Neuron. 114, 16, p. 3061-3076.e7Research output: Contribution to journal › Article › peer-review
Open Access -
Neural circuit mechanisms underlying aberrantly prolonged functional hyperemia in young Alzheimer’s disease mice
Kim, T. A., Cruz, G., Syty, M. D., Wang, F., Wang, X., Duan, A., Halterman, M., Xiong, Q., Palop, J. J. & Ge, S., Feb 2025, In: Molecular Psychiatry. 30, 2, p. 367-378 12 p., 11934.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Hypothalamic-Modified New Hippocampal Neurons for Alzheimer’s Disease
Gu, Y. & Ge, S., Nov 2023, In: Neuroscience Bulletin. 39, 11, p. 1735-1737 3 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging
Nasu, Y., Aggarwal, A., Le, G. N. T., Vo, C. T., Kambe, Y., Wang, X., Beinlich, F. R. M., Lee, A. B., Ram, T. R., Wang, F., Gorzo, K. A., Kamijo, Y., Boisvert, M., Nishinami, S., Kawamura, G., Ozawa, T., Toda, H., Gordon, G. R., Ge, S. & Hirase, H. & 5 others, , Dec 2023, In: Nature Communications. 14, 1, 6598.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Nigrostriatal dopamine modulates the striatal-amygdala pathway in auditory fear conditioning
Chen, A. P. F., Chen, L., Shi, K. W., Cheng, E., Ge, S. & Xiong, Q., Dec 2023, In: Nature Communications. 14, 1, 7231.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations