Grants & Projects per year
Personal profile
Research interests
Biochemical, structural, and mechanistic explorations of protein and RNA homeostasis
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Collaborations and top research areas from the last five years
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Graduate Research Funds: Max Henderson & Daniel Wong Gutierrez: AlkB Structure and Function
Karzai, W. (CoPI) & Liu, Q. (PI)
03/17/26 → 12/31/26
Project: Research
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Grad Student Support for Max Henderson: Machine Learning/Artificial Intelligence for Quantitative Plant Biology: Structural Determinants of Host Pathogen Interactions
Karzai, W. (PI) & Yu, X. (CoPI)
03/28/23 → 09/30/23
Project: Research
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Quality Control Mechanisms in Protein Synthesis
Karzai, W. (PI)
National Institute of General Medical Sciences
09/21/22 → 07/31/26
Project: Research
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The Role the AAA+ Lon Proteases in Bacterial Pathogenesis
Karzai, W. (PI) & Benach, J. (CoPI)
National Institute of Allergy & Infectious Disease
06/1/17 → 05/31/24
Project: Research
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ARRA: Agents of Bioterrorism: Pathogenesis and Host Defense
Benach, J. (PI), Furie, M. (CoI), Karzai, W. (CoI), Mackow, E. (CoI), Thanassi, D. G. (CoI), van der Velden, A. (CoI) & Bliska, J. (CoI)
National Institute of Allergy & Infectious Disease
08/1/10 → 06/30/13
Project: Research
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Substrate recognition and cleavage-site preferences of Lon protease
Cragan, M., Puri, N. & Karzai, A. W., Apr 2025, In: Journal of Biological Chemistry. 301, 4, 108365.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Endogenous and borrowed proteolytic activity in the borrelia
Coleman, J. L., Benach, J. L. & Wali Karzai, A., 2021, In: Microbiology and Molecular Biology Reviews. 85, 2, e00217-20.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations -
Structural basis for distinct operational modes and protease activation in aaa+ protease lon
Shin, M., Shin, M., Puchades, C., Puchades, C., Asmita, A., Puri, N., Adjei, E., Wiseman, R. L., Karzai, A. W. & Lander, G. C., May 2020, In: Science Advances. 6, 21, EABA8404.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
HspQ Functions as a Unique Specificity-Enhancing Factor for the AAA+ Lon Protease
Puri, N. & Karzai, A. W., Jun 1 2017, In: Molecular Cell. 66, 5, p. 672-683.e4Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
The effect of pyrite on Escherichia coli in water: Proof-of-concept for the elimination of waterborne bacteria by reactive minerals
Friedlander, L. R., Puri, N., Schoonen, M. A. A. & Karzai, A. W., 2015, In: Journal of Water and Health. 13, 1, p. 42-53 12 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations