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Wei Yang

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Wei Yang

 https://orcid.org/0000-0003-2575-3570
    20082026

    Research activity per year

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    Research interests

    The Yang lab focuses on harnessing the power of multi-level proteomics technologies, such as global proteomics, phosphoproteomics, palmitoyl-proteomics, interactome profiling, thermal proteome profiling, and targeted proteomics, to delineate the molecular mechanisms of cancer metastasis. The ultimate goal is to identify promising drug targets and reliable biomarkers, enabling precision treatment of patients facing a high risk of metastatic progression.

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    • A RIPK2 activity signature in prostate cancer: Modulation by RIPK2 inhibition and clinical association

      Elgehama, A. M., Yang, Q., Pires Sanches, J. G., He, Z., Ruegg, L., You, S. & Yang, W., Jul 2026, In: Translational Oncology. 69, 102819.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Extracellular vesicle heterogeneity through the lens of multiomics

      Silva, T. F., Hutchins, E., Zhao, W., Ciani, Y., Kim, M., Ko, E., Mariscal, J., Qiu, Z., Bedier, F., Kittel, A., Zhou, B., Wang, Y., Hall, M., Galasso, F., Reiman, R., Freeman, M. R., Parker, S., Van Eyk, J., Yang, W. & Posadas, E. & 10 others, Guarnerio, J., Nolan, J., Théry, C., Zijlstra, A., Stott, S., You, S., Demichelis, F., Boutros, P. C., Van Keuren-Jensen, K. & Di Vizio, D., Jul 15 2025, In: Cell Reports Medicine. 6, 7, 102161.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      40 Scopus citations

    • Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury

      Gheinani, A. H., Sack, B. S., Bigger-Allen, A., Thaker, H., Atta, H., Lambrinos, G., Costa, K., Doyle, C., Gharaee-Kermani, M., Patalano, S., Piper, M., Cotellessa, J. F., Vitko, D., Li, H., Prabhakaran, M. K., Cristofaro, V., Froehlich, J., Lee, R. S., Yang, W. & Sullivan, M. P. & 2 others, Macoska, J. A. & Adam, R. M., Jun 2025, In: JCI Insight. 10, 12, e180275.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations

    • ONECUT2 acts as a lineage plasticity driver in adenocarcinoma as well as neuroendocrine variants of prostate cancer

      Qian, C., Yang, Q., Rotinen, M., Huang, R., Kim, H., Gallent, B., Yan, Y., Cadaneanu, R. M., Zhang, B., Kaochar, S., Freedland, S. J., Posadas, E. M., Ellis, L., Vizio, D. D., Morrissey, C., Nelson, P. S., Brady, L., Murali, R., Campbell, M. J. & Yang, W. & 6 others, Knudsen, B. S., Mostaghel, E. A., Ye, H., Garraway, I. P., You, S. & Freeman, M. R., Jul 22 2024, In: Nucleic Acids Research. 52, 13, p. 7740-7760 21 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      40 Scopus citations

    • Profiling phagosome proteins identifies PD-L1 as a fungal-binding receptor

      Li, K., Chatterjee, A., Qian, C., Lagree, K., Wang, Y., Becker, C. A., Freeman, M. R., Murali, R., Yang, W. & Underhill, D. M., Jun 20 2024, In: Nature. 630, 8017, p. 736-743 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      33 Scopus citations
    View all 50 Research outputs