2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Leslie L. Davis; Michelle M. Kittleson; Jamil A. Aboulhosn; Paul Khairy; Yuli Y. Kim; Kathryn A. Osteen; Puja B. Parikh; Rachel L. Schunder

doi:10.1161/CIR.0000000000001402

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Leslie L. Davis
, Michelle M. Kittleson
, Jamil A. Aboulhosn
, Paul Khairy
, Yuli Y. Kim
, Kathryn A. Osteen
, Puja B. Parikh
, Rachel L. Schunder

Department of Medicine - Division of Cardiology

ACC/AHA Joint Committee on Clinical Practice Guidelines liaison.
Former Joint Committee on Clinical Practice Guidelines member; current member during the writing effort.
Society for Cardiovascular Angiography and Interventions representative.
Heart Rhythm Society representative.
International Society for Adult Congenital Heart Disease representative.
Patient representative.
Joint AHA/ACC staff representative.

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

AIM – The “2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease” provides recommendations to guide clinicians on the evaluation and treatment of adult patients with congenital heart disease. It incorporates new evidence to replace the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease.” METHODS – A comprehensive literature search was conducted with a focus on literature published from 2017 to 2024; in some instances, older literature was also collected and reviewed. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants and published in English were identified from MEDLINE (via PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and CINAHL for selected searches. STRUCTURE – Recommendations from the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease” have been updated with new evidence to guide clinicians.

Original language	English
Journal	Circulation
DOIs	https://doi.org/10.1161/CIR.0000000000001402
State	Published - 2025

Keywords

AHA Scientific Statements
Ebstein anomaly
adult congenital heart disease
aortic coarctation
aortic valve stenosis
cardiac catheterization
cardiac surgical procedures
congenital heart disease
cor triatriatum
coronary vessel anomalies
diagnostic imaging
discrete subaortic stenosis
ductus arteriosus
follow-up studies
heart defects, congenital
heart septal defects, ventricular, mortality
patent
pulmonary valve stenosis
reoperation
surgery
survival rate
tetralogy of Fallot
therapy
transposition of great vessels
treatment outcome
ventricular outflow obstruction

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Davis, L. L., Kittleson, M. M., Aboulhosn, J. A., Khairy, P., Kim, Y. Y., Osteen, K. A., Parikh, P. B., & Schunder, R. L. (2025). 2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. https://doi.org/10.1161/CIR.0000000000001402

@article{d5dfb3185ed24069980929c36b6726ac,

title = "2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines",

abstract = "AIM – The “2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease” provides recommendations to guide clinicians on the evaluation and treatment of adult patients with congenital heart disease. It incorporates new evidence to replace the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease.” METHODS – A comprehensive literature search was conducted with a focus on literature published from 2017 to 2024; in some instances, older literature was also collected and reviewed. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants and published in English were identified from MEDLINE (via PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and CINAHL for selected searches. STRUCTURE – Recommendations from the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease” have been updated with new evidence to guide clinicians.",

keywords = "AHA Scientific Statements, Ebstein anomaly, adult congenital heart disease, aortic coarctation, aortic valve stenosis, cardiac catheterization, cardiac surgical procedures, congenital heart disease, cor triatriatum, coronary vessel anomalies, diagnostic imaging, discrete subaortic stenosis, ductus arteriosus, follow-up studies, heart defects, congenital, heart septal defects, ventricular, mortality, patent, pulmonary valve stenosis, reoperation, surgery, survival rate, tetralogy of Fallot, therapy, transposition of great vessels, treatment outcome, ventricular outflow obstruction",

author = "Davis, \{Leslie L.\} and Kittleson, \{Michelle M.\} and Aboulhosn, \{Jamil A.\} and Paul Khairy and Kim, \{Yuli Y.\} and Osteen, \{Kathryn A.\} and Parikh, \{Puja B.\} and Schunder, \{Rachel L.\}",

note = "Publisher Copyright: {\textcopyright} 2025",

year = "2025",

doi = "10.1161/CIR.0000000000001402",

language = "English",

journal = "Circulation",

issn = "0009-7322",

}

Davis, LL, Kittleson, MM, Aboulhosn, JA, Khairy, P, Kim, YY, Osteen, KA, Parikh, PB & Schunder, RL 2025, '2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines', Circulation. https://doi.org/10.1161/CIR.0000000000001402

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. / Davis, Leslie L.; Kittleson, Michelle M.; Aboulhosn, Jamil A. et al.
In: Circulation, 2025.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - 2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease

T2 - A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

AU - Davis, Leslie L.

AU - Kittleson, Michelle M.

AU - Aboulhosn, Jamil A.

AU - Khairy, Paul

AU - Kim, Yuli Y.

AU - Osteen, Kathryn A.

AU - Parikh, Puja B.

AU - Schunder, Rachel L.

PY - 2025

Y1 - 2025

N2 - AIM – The “2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease” provides recommendations to guide clinicians on the evaluation and treatment of adult patients with congenital heart disease. It incorporates new evidence to replace the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease.” METHODS – A comprehensive literature search was conducted with a focus on literature published from 2017 to 2024; in some instances, older literature was also collected and reviewed. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants and published in English were identified from MEDLINE (via PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and CINAHL for selected searches. STRUCTURE – Recommendations from the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease” have been updated with new evidence to guide clinicians.

AB - AIM – The “2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease” provides recommendations to guide clinicians on the evaluation and treatment of adult patients with congenital heart disease. It incorporates new evidence to replace the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease.” METHODS – A comprehensive literature search was conducted with a focus on literature published from 2017 to 2024; in some instances, older literature was also collected and reviewed. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants and published in English were identified from MEDLINE (via PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and CINAHL for selected searches. STRUCTURE – Recommendations from the “2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease” have been updated with new evidence to guide clinicians.

KW - AHA Scientific Statements

KW - Ebstein anomaly

KW - adult congenital heart disease

KW - aortic coarctation

KW - aortic valve stenosis

KW - cardiac catheterization

KW - cardiac surgical procedures

KW - congenital heart disease

KW - cor triatriatum

KW - coronary vessel anomalies

KW - diagnostic imaging

KW - discrete subaortic stenosis

KW - ductus arteriosus

KW - follow-up studies

KW - heart defects, congenital

KW - heart septal defects, ventricular, mortality

KW - patent

KW - pulmonary valve stenosis

KW - reoperation

KW - surgery

KW - survival rate

KW - tetralogy of Fallot

KW - therapy

KW - transposition of great vessels

KW - treatment outcome

KW - ventricular outflow obstruction

UR - https://www.scopus.com/pages/publications/105027699438

U2 - 10.1161/CIR.0000000000001402

DO - 10.1161/CIR.0000000000001402

M3 - Review article

C2 - 41411375

AN - SCOPUS:105027699438

SN - 0009-7322

JO - Circulation

JF - Circulation

ER -

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Abstract

Keywords

Access to Document

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