A cell impedance sensor based on a silicon cochlea

Tara Julia Hamilton; Nicole M. Nelson; David Sander; Pamela Abshire

doi:10.1109/BIOCAS.2009.5372071

A cell impedance sensor based on a silicon cochlea

Tara Julia Hamilton
, Nicole M. Nelson
, David Sander
, Pamela Abshire

Electrical Engineering

University of Queensland
University of Maryland, College Park

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

10 Scopus citations

Abstract

In this paper, we present the design of an integrated CMOS sensor for cell impedance measurement. To achieve simultaneous measurements over a wide frequency range, the impedance sensor has been developed using silicon cochleae as both the input stimulus generator and the output frequency analyzer. This solution, inspired by the accuracy and efficiency of biological systems, has several advantages. The silicon cochlea is able to make measurements over a very wide frequency range (from Hz to MHz) with variable resolution. Power consumption of the sensor is below 30μW due to the biasing regime used in the silicon cochleae. Furthermore, the implementation of the sensor is fully autonomous requiring no reference clocks or signal generators, facilitating integration into larger cell analysis systems.

Original language	English
Title of host publication	2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009
Pages	117-120
Number of pages	4
DOIs	https://doi.org/10.1109/BIOCAS.2009.5372071
State	Published - 2009
Event	2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009 - Beijing, China Duration: Nov 26 2009 → Nov 28 2009

Publication series

Name	2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009

Conference

Conference	2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009
Country/Territory	China
City	Beijing
Period	11/26/09 → 11/28/09

Access to Document

10.1109/BIOCAS.2009.5372071

Cite this

@inproceedings{9be41f51e75e4564b70fb108a23812ac,

title = "A cell impedance sensor based on a silicon cochlea",

abstract = "In this paper, we present the design of an integrated CMOS sensor for cell impedance measurement. To achieve simultaneous measurements over a wide frequency range, the impedance sensor has been developed using silicon cochleae as both the input stimulus generator and the output frequency analyzer. This solution, inspired by the accuracy and efficiency of biological systems, has several advantages. The silicon cochlea is able to make measurements over a very wide frequency range (from Hz to MHz) with variable resolution. Power consumption of the sensor is below 30μW due to the biasing regime used in the silicon cochleae. Furthermore, the implementation of the sensor is fully autonomous requiring no reference clocks or signal generators, facilitating integration into larger cell analysis systems.",

author = "Hamilton, \{Tara Julia\} and Nelson, \{Nicole M.\} and David Sander and Pamela Abshire",

year = "2009",

doi = "10.1109/BIOCAS.2009.5372071",

language = "English",

isbn = "9781424449187",

series = "2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009",

pages = "117--120",

booktitle = "2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009",

note = "2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009 ; Conference date: 26-11-2009 Through 28-11-2009",

}

Hamilton, TJ, Nelson, NM, Sander, D & Abshire, P 2009, A cell impedance sensor based on a silicon cochlea. in 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009., 5372071, 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009, pp. 117-120, 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009, Beijing, China, 11/26/09. https://doi.org/10.1109/BIOCAS.2009.5372071

A cell impedance sensor based on a silicon cochlea. / Hamilton, Tara Julia; Nelson, Nicole M.; Sander, David et al.
2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009. 2009. p. 117-120 5372071 (2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A cell impedance sensor based on a silicon cochlea

AU - Hamilton, Tara Julia

AU - Nelson, Nicole M.

AU - Sander, David

AU - Abshire, Pamela

PY - 2009

Y1 - 2009

N2 - In this paper, we present the design of an integrated CMOS sensor for cell impedance measurement. To achieve simultaneous measurements over a wide frequency range, the impedance sensor has been developed using silicon cochleae as both the input stimulus generator and the output frequency analyzer. This solution, inspired by the accuracy and efficiency of biological systems, has several advantages. The silicon cochlea is able to make measurements over a very wide frequency range (from Hz to MHz) with variable resolution. Power consumption of the sensor is below 30μW due to the biasing regime used in the silicon cochleae. Furthermore, the implementation of the sensor is fully autonomous requiring no reference clocks or signal generators, facilitating integration into larger cell analysis systems.

AB - In this paper, we present the design of an integrated CMOS sensor for cell impedance measurement. To achieve simultaneous measurements over a wide frequency range, the impedance sensor has been developed using silicon cochleae as both the input stimulus generator and the output frequency analyzer. This solution, inspired by the accuracy and efficiency of biological systems, has several advantages. The silicon cochlea is able to make measurements over a very wide frequency range (from Hz to MHz) with variable resolution. Power consumption of the sensor is below 30μW due to the biasing regime used in the silicon cochleae. Furthermore, the implementation of the sensor is fully autonomous requiring no reference clocks or signal generators, facilitating integration into larger cell analysis systems.

UR - https://www.scopus.com/pages/publications/77749345929

U2 - 10.1109/BIOCAS.2009.5372071

DO - 10.1109/BIOCAS.2009.5372071

M3 - Conference contribution

AN - SCOPUS:77749345929

SN - 9781424449187

T3 - 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009

SP - 117

EP - 120

BT - 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009

T2 - 2009 IEEE Biomedical Circuits and Systems Conference, BioCAS 2009

Y2 - 26 November 2009 through 28 November 2009

ER -

A cell impedance sensor based on a silicon cochlea

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