A chemical reporter strategy to probe glycoprotein fucosylation

David Rabuka; Sarah C. Hubbard; Scott T. Laughlin; Sulabha P. Argade; Carolyn R. Bertozzi

doi:10.1021/ja064619y

A chemical reporter strategy to probe glycoprotein fucosylation

David Rabuka
, Sarah C. Hubbard
, Scott T. Laughlin
, Sulabha P. Argade
, Carolyn R. Bertozzi

Chemistry

University of California at Berkeley
University of California at San Diego
Lawrence Berkeley National Laboratory

Research output: Contribution to journal › Article › peer-review

160 Scopus citations

Abstract

Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.

Original language	English
Pages (from-to)	12078-12079
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	128
Issue number	37
DOIs	https://doi.org/10.1021/ja064619y
State	Published - Sep 20 2006

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10.1021/ja064619y

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@article{bb6272eca02841aeb3a9c50f20aeae72,

title = "A chemical reporter strategy to probe glycoprotein fucosylation",

abstract = "Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.",

author = "David Rabuka and Hubbard, \{Sarah C.\} and Laughlin, \{Scott T.\} and Argade, \{Sulabha P.\} and Bertozzi, \{Carolyn R.\}",

year = "2006",

month = sep,

day = "20",

doi = "10.1021/ja064619y",

language = "English",

volume = "128",

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journal = "Journal of the American Chemical Society",

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T1 - A chemical reporter strategy to probe glycoprotein fucosylation

AU - Rabuka, David

AU - Hubbard, Sarah C.

AU - Laughlin, Scott T.

AU - Argade, Sulabha P.

AU - Bertozzi, Carolyn R.

PY - 2006/9/20

Y1 - 2006/9/20

N2 - Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.

AB - Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.

UR - https://www.scopus.com/pages/publications/33748782280

U2 - 10.1021/ja064619y

DO - 10.1021/ja064619y

M3 - Article

C2 - 16967952

AN - SCOPUS:33748782280

SN - 0002-7863

VL - 128

SP - 12078

EP - 12079

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 37

ER -

A chemical reporter strategy to probe glycoprotein fucosylation

Abstract

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