A facile synthetic method to prepare fluorescently labeled ROMP polymers

Kenny S. Roberts; Nicole S. Sampson

doi:10.1021/ol048935y

A facile synthetic method to prepare fluorescently labeled ROMP polymers

Kenny S. Roberts
, Nicole S. Sampson

Chemistry

Stony Brook University

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

(Chemical Equation Presented) To probe the activities of sperm ADAM protein (fertilinβ), we devised a general synthetic strategy to generate fluorescently labeled fertilinβ oligopeptide polymers. Immunofluorescence studies with these polymers demonstrated that fertilinβ polymers bind specifically to a protein receptor on the mouse egg plasma membrane.

Original language	English
Pages (from-to)	3253-3255
Number of pages	3
Journal	Organic Letters
Volume	6
Issue number	19
DOIs	https://doi.org/10.1021/ol048935y
State	Published - Sep 16 2004

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10.1021/ol048935y

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title = "A facile synthetic method to prepare fluorescently labeled ROMP polymers",

abstract = "(Chemical Equation Presented) To probe the activities of sperm ADAM protein (fertilinβ), we devised a general synthetic strategy to generate fluorescently labeled fertilinβ oligopeptide polymers. Immunofluorescence studies with these polymers demonstrated that fertilinβ polymers bind specifically to a protein receptor on the mouse egg plasma membrane.",

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year = "2004",

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T1 - A facile synthetic method to prepare fluorescently labeled ROMP polymers

AU - Roberts, Kenny S.

AU - Sampson, Nicole S.

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N2 - (Chemical Equation Presented) To probe the activities of sperm ADAM protein (fertilinβ), we devised a general synthetic strategy to generate fluorescently labeled fertilinβ oligopeptide polymers. Immunofluorescence studies with these polymers demonstrated that fertilinβ polymers bind specifically to a protein receptor on the mouse egg plasma membrane.

AB - (Chemical Equation Presented) To probe the activities of sperm ADAM protein (fertilinβ), we devised a general synthetic strategy to generate fluorescently labeled fertilinβ oligopeptide polymers. Immunofluorescence studies with these polymers demonstrated that fertilinβ polymers bind specifically to a protein receptor on the mouse egg plasma membrane.

UR - https://www.scopus.com/pages/publications/4644268453

U2 - 10.1021/ol048935y

DO - 10.1021/ol048935y

M3 - Article

C2 - 15355025

AN - SCOPUS:4644268453

SN - 1523-7060

VL - 6

SP - 3253

EP - 3255

JO - Organic Letters

JF - Organic Letters

IS - 19

ER -

A facile synthetic method to prepare fluorescently labeled ROMP polymers

Abstract

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