A fluorescent probe capable of detecting H2S at submicromolar concentrations in cells

Weimin Xuan; Rong Pan; Yanting Cao; Kejian Liu; Wei Wang

doi:10.1039/c2cc35602c

A fluorescent probe capable of detecting H₂S at submicromolar concentrations in cells

Weimin Xuan
, Rong Pan
, Yanting Cao
, Kejian Liu
, Wei Wang

Pathology

University of New Mexico

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H₂S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H₂S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H₂S at submicromolar concentrations in cells.

Original language	English
Pages (from-to)	10669-10671
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	86
DOIs	https://doi.org/10.1039/c2cc35602c
State	Published - Oct 3 2012

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10.1039/c2cc35602c

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title = "A fluorescent probe capable of detecting H2S at submicromolar concentrations in cells",

abstract = "A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H2S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H2S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H2S at submicromolar concentrations in cells.",

author = "Weimin Xuan and Rong Pan and Yanting Cao and Kejian Liu and Wei Wang",

year = "2012",

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doi = "10.1039/c2cc35602c",

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T1 - A fluorescent probe capable of detecting H2S at submicromolar concentrations in cells

AU - Xuan, Weimin

AU - Pan, Rong

AU - Cao, Yanting

AU - Liu, Kejian

AU - Wang, Wei

PY - 2012/10/3

Y1 - 2012/10/3

N2 - A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H2S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H2S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H2S at submicromolar concentrations in cells.

AB - A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H2S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H2S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H2S at submicromolar concentrations in cells.

UR - https://www.scopus.com/pages/publications/84867310943

U2 - 10.1039/c2cc35602c

DO - 10.1039/c2cc35602c

M3 - Article

C2 - 23010954

AN - SCOPUS:84867310943

SN - 1359-7345

VL - 48

SP - 10669

EP - 10671

JO - Chemical Communications

JF - Chemical Communications

IS - 86

ER -

A fluorescent probe capable of detecting H₂S at submicromolar concentrations in cells

Abstract

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