A new protecting group for the exocyclic amino groups of nucleosides

Chamakura V.N.S. Varaprasad; Francis Johnson

doi:10.1016/j.tetlet.2005.01.028

A new protecting group for the exocyclic amino groups of nucleosides

Chamakura V.N.S. Varaprasad
, Francis Johnson

Pharmacological Sciences

Stony Brook University
Valeant Pharmaceuticals International

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A new protecting group has been developed for the exocyclic amino groups of nucleosides that occur in DNA. 3-Phenyl-[{N-(2-trimethylsilyl-ethoxycarbonyl)- 2-amino}]-propanoic acid used as the protective agent.

Original language	English
Pages (from-to)	2163-2165
Number of pages	3
Journal	Tetrahedron Letters
Volume	46
Issue number	12
DOIs	https://doi.org/10.1016/j.tetlet.2005.01.028
State	Published - Mar 21 2005

Keywords

Deoxy nucleosides
Protecting groups

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10.1016/j.tetlet.2005.01.028

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title = "A new protecting group for the exocyclic amino groups of nucleosides",

abstract = "A new protecting group has been developed for the exocyclic amino groups of nucleosides that occur in DNA. 3-Phenyl-[\{N-(2-trimethylsilyl-ethoxycarbonyl)- 2-amino\}]-propanoic acid used as the protective agent.",

keywords = "Deoxy nucleosides, Protecting groups",

author = "Varaprasad, \{Chamakura V.N.S.\} and Francis Johnson",

year = "2005",

month = mar,

day = "21",

doi = "10.1016/j.tetlet.2005.01.028",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - A new protecting group for the exocyclic amino groups of nucleosides

AU - Varaprasad, Chamakura V.N.S.

AU - Johnson, Francis

PY - 2005/3/21

Y1 - 2005/3/21

N2 - A new protecting group has been developed for the exocyclic amino groups of nucleosides that occur in DNA. 3-Phenyl-[{N-(2-trimethylsilyl-ethoxycarbonyl)- 2-amino}]-propanoic acid used as the protective agent.

AB - A new protecting group has been developed for the exocyclic amino groups of nucleosides that occur in DNA. 3-Phenyl-[{N-(2-trimethylsilyl-ethoxycarbonyl)- 2-amino}]-propanoic acid used as the protective agent.

KW - Deoxy nucleosides

KW - Protecting groups

UR - https://www.scopus.com/pages/publications/14644417198

U2 - 10.1016/j.tetlet.2005.01.028

DO - 10.1016/j.tetlet.2005.01.028

M3 - Article

AN - SCOPUS:14644417198

SN - 0040-4039

VL - 46

SP - 2163

EP - 2165

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 12

ER -

A new protecting group for the exocyclic amino groups of nucleosides

Abstract

Keywords

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