A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones

Iwao Ojima; Shigemi Suga; Rumiko Abe

doi:10.1016/0040-4039(80)80213-9

A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones

Iwao Ojima
, Shigemi Suga
, Rumiko Abe

Chemistry

Sagami Chemical Research Institute

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

1-(1-Methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones were found to be cleaved exclusively at the NC⁴ bond by the hydrogenolysis on palladium catalyst to give the corresponding dipeptide and its derivative in excellent yields.

Original language	English
Pages (from-to)	3907-3910
Number of pages	4
Journal	Tetrahedron Letters
Volume	21
Issue number	40
DOIs	https://doi.org/10.1016/0040-4039(80)80213-9
State	Published - 1980

Access to Document

10.1016/0040-4039(80)80213-9

Cite this

@article{9d9a16c556094801ac4a4ae0852017c7,

title = "A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones",

abstract = "1-(1-Methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones were found to be cleaved exclusively at the NC4 bond by the hydrogenolysis on palladium catalyst to give the corresponding dipeptide and its derivative in excellent yields.",

author = "Iwao Ojima and Shigemi Suga and Rumiko Abe",

year = "1980",

doi = "10.1016/0040-4039(80)80213-9",

language = "English",

volume = "21",

pages = "3907--3910",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "40",

}

TY - JOUR

T1 - A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones

AU - Ojima, Iwao

AU - Suga, Shigemi

AU - Abe, Rumiko

PY - 1980

Y1 - 1980

N2 - 1-(1-Methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones were found to be cleaved exclusively at the NC4 bond by the hydrogenolysis on palladium catalyst to give the corresponding dipeptide and its derivative in excellent yields.

AB - 1-(1-Methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones were found to be cleaved exclusively at the NC4 bond by the hydrogenolysis on palladium catalyst to give the corresponding dipeptide and its derivative in excellent yields.

UR - https://www.scopus.com/pages/publications/0001163944

U2 - 10.1016/0040-4039(80)80213-9

DO - 10.1016/0040-4039(80)80213-9

M3 - Article

AN - SCOPUS:0001163944

SN - 0040-4039

VL - 21

SP - 3907

EP - 3910

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 40

ER -

A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones

Abstract

Access to Document

Other files and links

Fingerprint

Cite this