Abstract
The concept of lipids acting as signaling and regulatory molecules is now taken for granted. However 3-4 decades ago, this was a rather unthinkable proposition even though the "writing was on the wall" since at least the 1950s. Here, I summarize briefly key historical landmarks in the evolution of the field of bioactive lipids and then describe studies from my group over 3 decades, focusing on the contemporaneous development of understanding of bioactive sphingolipids.
| Original language | English |
|---|---|
| Pages (from-to) | 1814-1831 |
| Number of pages | 18 |
| Journal | European Journal of Lipid Science and Technology |
| Volume | 117 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2015 |
Keywords
- Ceramide
- Phosphatase
- Sphingolipids
- Sphingomyelinase
- Sphingosine
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