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Antiplatelet therapy in neuroendovascular therapeutics

  • David Fiorella
  • , Lucie Thiabolt
  • , Felipe C. Albuquerque
  • , Vivek R. Deshmukh
  • , Cameron G. McDougall
  • , Peter A. Rasmussen
  • Boston Scientific Neurovascular
  • St. Joseph's Hospital and Medical Center, Phoenix
  • Cleveland Clinic Foundation

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations

Abstract

Our understanding of the pharmacology of antiplatelet therapy continues to evolve rapidly. Although the existing data are primarily generated in the setting of interventional and preventative cardiology studies, these data may be extrapolated to guide the rational application of these agents in neuroendovascular procedures. Platelet function testing represents an increasingly available and practical method by which to verify the adequacy of therapy and guide clinical decision making. The optimal application of these agents will undoubtedly improve the risk profile of neuroendovascular procedures, increase the success rate of acute stroke intervention, and facilitate more effective secondary stroke prevention.

Original languageEnglish
Pages (from-to)517-540
Number of pages24
JournalNeurosurgery Clinics of North America
Volume16
Issue number3
DOIs
StatePublished - Jul 2005

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