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Appearance, site of occurrence, and physical and clinical characteristics of oral carcinoma in Torino, Italy

  • Arthur Mashberg
  • , Franco Merletti
  • , Paolo Boffetta
  • , Sergio Gandolfo
  • , Franca Ozzello
  • , Fabrizio Fracchia
  • , Benedetto Terracini
  • VA Medical Center
  • Rutgers - The State University of New Jersey, New Brunswick
  • Dipartimento di Scienze biomediche e oncologia umana
  • University of Turin
  • Ospedale San Giovanni Vecchio

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

The appearance, site of occurrence, and selected physical and clinical characteristics are reported for 102 symptomatic carcinomas diagnosed during a 30‐month period in Torino, Italy. Erythroplasia was a more significant visual component than leukoplakia, confirming the results of a previous study on asymptomatic cancer in a US population. Floor of the mouth, oral tongue, and soft palate complex accounted for 75% of all sites and 84% of sites if posterior pillar is excluded. Seventeen percent of the lesions were T1, 60% T2, and 23% larger than T2. Size of the lesion was associated with anterior or posterior position and the mobility of the structure, as well as with ulceration, bleeding, and lymphadenopathy (55% of cancers had no nodal involvement). Tumefaction, burning, and pain were the most frequently reported symptoms. About 50% of patients experienced a time lapse between onset of symptoms and final diagnosis of less than 3 months, and this proportion was higher among patients with T1 cancers.

Original languageEnglish
Pages (from-to)2522-2527
Number of pages6
JournalCancer
Volume63
Issue number12
DOIs
StatePublished - Jun 15 1989

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