Application of iron-tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide with p-hydroxyphenylpropionic acid as a substrate

Qiu Ying Chen; Dong Hui Li; Qing Zhi Zhu; Hong Zheng; Jin Gou Xu

doi:10.1016/S0003-2670(98)00743-0

Application of iron-tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide with p-hydroxyphenylpropionic acid as a substrate

Qiu Ying Chen
, Dong Hui Li
, Qing Zhi Zhu
, Hong Zheng
, Jin Gou Xu

Office of the Dean SOMAS

Xiamen University

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

A new promising mimetic peroxidase, iron-tetrasulfonatophthalocyanine (FeTSPC), has been synthesized and applied to the determination of hydrogen peroxide based on its catalytic effect on the oxidation of p-hydroxyphenylpropionic acid (p-HPPA). Under optimum conditions, the calibration graph has a linear range of 0.0 x 10^-6 - 3.6 x 10^-6 mol/l hydrogen peroxide with a detection limit of 1.3 x 10^-8 mol/l in a 30 min reaction period. Application of the system to the determination of glucose shows a linear range 0.0 x 10^-6 - 6.0 x 10^-6 mol/l and a detection limit of 3.1 x 10^-8 mol/l. The feasibility of FeTSPC as a new mimetic peroxidase in practical clinical analysis has been proven in the determination of glucose in human serum.

Original language	English
Pages (from-to)	175-182
Number of pages	8
Journal	Analytica Chimica Acta
Volume	381
Issue number	2-3
DOIs	https://doi.org/10.1016/S0003-2670(98)00743-0
State	Published - Feb 16 1999

Keywords

Fluorimetry
Hydrogen peroxide determination
Iron-tetrasulfonatophthalocyanine
Mimetic enzyme

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10.1016/S0003-2670(98)00743-0

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@article{9184e4f990cc444db5c68acb352ad62e,

title = "Application of iron-tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide with p-hydroxyphenylpropionic acid as a substrate",

abstract = "A new promising mimetic peroxidase, iron-tetrasulfonatophthalocyanine (FeTSPC), has been synthesized and applied to the determination of hydrogen peroxide based on its catalytic effect on the oxidation of p-hydroxyphenylpropionic acid (p-HPPA). Under optimum conditions, the calibration graph has a linear range of 0.0 x 10-6 - 3.6 x 10-6 mol/l hydrogen peroxide with a detection limit of 1.3 x 10-8 mol/l in a 30 min reaction period. Application of the system to the determination of glucose shows a linear range 0.0 x 10-6 - 6.0 x 10-6 mol/l and a detection limit of 3.1 x 10-8 mol/l. The feasibility of FeTSPC as a new mimetic peroxidase in practical clinical analysis has been proven in the determination of glucose in human serum.",

keywords = "Fluorimetry, Hydrogen peroxide determination, Iron-tetrasulfonatophthalocyanine, Mimetic enzyme",

author = "Chen, \{Qiu Ying\} and Li, \{Dong Hui\} and Zhu, \{Qing Zhi\} and Hong Zheng and Xu, \{Jin Gou\}",

year = "1999",

month = feb,

day = "16",

doi = "10.1016/S0003-2670(98)00743-0",

language = "English",

volume = "381",

pages = "175--182",

journal = "Analytica Chimica Acta",

issn = "0003-2670",

number = "2-3",

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TY - JOUR

T1 - Application of iron-tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide with p-hydroxyphenylpropionic acid as a substrate

AU - Chen, Qiu Ying

AU - Li, Dong Hui

AU - Zhu, Qing Zhi

AU - Zheng, Hong

AU - Xu, Jin Gou

PY - 1999/2/16

Y1 - 1999/2/16

N2 - A new promising mimetic peroxidase, iron-tetrasulfonatophthalocyanine (FeTSPC), has been synthesized and applied to the determination of hydrogen peroxide based on its catalytic effect on the oxidation of p-hydroxyphenylpropionic acid (p-HPPA). Under optimum conditions, the calibration graph has a linear range of 0.0 x 10-6 - 3.6 x 10-6 mol/l hydrogen peroxide with a detection limit of 1.3 x 10-8 mol/l in a 30 min reaction period. Application of the system to the determination of glucose shows a linear range 0.0 x 10-6 - 6.0 x 10-6 mol/l and a detection limit of 3.1 x 10-8 mol/l. The feasibility of FeTSPC as a new mimetic peroxidase in practical clinical analysis has been proven in the determination of glucose in human serum.

AB - A new promising mimetic peroxidase, iron-tetrasulfonatophthalocyanine (FeTSPC), has been synthesized and applied to the determination of hydrogen peroxide based on its catalytic effect on the oxidation of p-hydroxyphenylpropionic acid (p-HPPA). Under optimum conditions, the calibration graph has a linear range of 0.0 x 10-6 - 3.6 x 10-6 mol/l hydrogen peroxide with a detection limit of 1.3 x 10-8 mol/l in a 30 min reaction period. Application of the system to the determination of glucose shows a linear range 0.0 x 10-6 - 6.0 x 10-6 mol/l and a detection limit of 3.1 x 10-8 mol/l. The feasibility of FeTSPC as a new mimetic peroxidase in practical clinical analysis has been proven in the determination of glucose in human serum.

KW - Fluorimetry

KW - Hydrogen peroxide determination

KW - Iron-tetrasulfonatophthalocyanine

KW - Mimetic enzyme

UR - https://www.scopus.com/pages/publications/0033044735

U2 - 10.1016/S0003-2670(98)00743-0

DO - 10.1016/S0003-2670(98)00743-0

M3 - Article

AN - SCOPUS:0033044735

SN - 0003-2670

VL - 381

SP - 175

EP - 182

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

IS - 2-3

ER -

Application of iron-tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide with p-hydroxyphenylpropionic acid as a substrate

Abstract

Keywords

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