Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam.

Iwao Ojima; Yazhong Pei

doi:10.1016/S0040-4039(00)94407-1

Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam.

Iwao Ojima
, Yazhong Pei

Chemistry

Stony Brook University

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and an applcation to the asymmetric synthesis of α,β-diamino acid and alcohol are described. Possible mechanisms for these reactions are proposed.

Original language	English
Pages (from-to)	977-980
Number of pages	4
Journal	Tetrahedron Letters
Volume	31
Issue number	7
DOIs	https://doi.org/10.1016/S0040-4039(00)94407-1
State	Published - 1990

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@article{72ddf606adc344c2b97b998fb08cbd25,

title = "Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam.",

abstract = "Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and an applcation to the asymmetric synthesis of α,β-diamino acid and alcohol are described. Possible mechanisms for these reactions are proposed.",

author = "Iwao Ojima and Yazhong Pei",

year = "1990",

doi = "10.1016/S0040-4039(00)94407-1",

language = "English",

volume = "31",

pages = "977--980",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "7",

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TY - JOUR

T1 - Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam.

AU - Ojima, Iwao

AU - Pei, Yazhong

PY - 1990

Y1 - 1990

N2 - Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and an applcation to the asymmetric synthesis of α,β-diamino acid and alcohol are described. Possible mechanisms for these reactions are proposed.

AB - Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and an applcation to the asymmetric synthesis of α,β-diamino acid and alcohol are described. Possible mechanisms for these reactions are proposed.

UR - https://www.scopus.com/pages/publications/0025177192

U2 - 10.1016/S0040-4039(00)94407-1

DO - 10.1016/S0040-4039(00)94407-1

M3 - Article

AN - SCOPUS:0025177192

SN - 0040-4039

VL - 31

SP - 977

EP - 980

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam.

Abstract

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