Autoinflammatory Disease

Brianne Navetta-Modrov; Apostolos Kontzias; Qingping Yao

doi:10.1007/978-3-030-80699-6_12

Autoinflammatory Disease

Brianne Navetta-Modrov
, Apostolos Kontzias
, Qingping Yao

Allergy and Immunology

Stony Brook University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Autoinflammatory diseases are a heterogeneous group of disorders characterized by abnormal activation of the innate immune system. They are an entity distinct from autoimmune disease and primary immunodeficiency disease, but at times patients may have overlapping immunologic and clinical features. They include monogenic and polygenic disorders, and molecular genetics can aid in making the diagnosis. This chapter will focus on the pathophysiology, clinical phenotype, diagnosis, and treatment of hereditary periodic fever syndromes and NOD2-associated diseases.

Original language	English
Title of host publication	Rheumatology for Primary Care Providers
Subtitle of host publication	A Clinical Casebook
Publisher	Springer International Publishing
Pages	293-310
Number of pages	18
ISBN (Electronic)	9783030806996
ISBN (Print)	9783030806989
DOIs	https://doi.org/10.1007/978-3-030-80699-6_12
State	Published - Jan 1 2021

Keywords

Autoinflammatory disease
Inflammation
NOD2
NOD2-associated disease
Periodic fever syndrome

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10.1007/978-3-030-80699-6_12

Cite this

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KW - Inflammation

KW - NOD2

KW - NOD2-associated disease

KW - Periodic fever syndrome

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Autoinflammatory Disease

Abstract

Keywords

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