Biodistribution and radiation dosimetry of C-harmine in baboons

Rajan Murthy; Kjell Erlandsson; Dileep Kumar; Ronald Van Heertum; John Mann; Ramin Parsey

doi:10.1097/MNM.0b013e32827420b5

Biodistribution and radiation dosimetry of C-harmine in baboons

Rajan Murthy
, Kjell Erlandsson
, Dileep Kumar
, Ronald Van Heertum
, John Mann
, Ramin Parsey

Psychiatry

Columbia University

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Monoamine oxidase A is a mitochondrial enzyme which is responsible for the metabolism of catecholamines such as dopamine, norepinephrine, as well as serotonin. This study describes the biodistribution and dosimetry of C-harmine, a tracer designed to specifically bind to monoamine oxidase A for positron emission tomography imaging.

Original language	English
Pages (from-to)	748-754
Number of pages	7
Journal	Nuclear Medicine Communications
Volume	28
Issue number	9
DOIs	https://doi.org/10.1097/MNM.0b013e32827420b5
State	Published - Sep 2007

Keywords

Baboon
Dosimetry
Monoamine oxidase-A
Positron emission tomography

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10.1097/MNM.0b013e32827420b5

Cite this

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abstract = "Monoamine oxidase A is a mitochondrial enzyme which is responsible for the metabolism of catecholamines such as dopamine, norepinephrine, as well as serotonin. This study describes the biodistribution and dosimetry of C-harmine, a tracer designed to specifically bind to monoamine oxidase A for positron emission tomography imaging.",

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AU - Mann, John

AU - Parsey, Ramin

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AB - Monoamine oxidase A is a mitochondrial enzyme which is responsible for the metabolism of catecholamines such as dopamine, norepinephrine, as well as serotonin. This study describes the biodistribution and dosimetry of C-harmine, a tracer designed to specifically bind to monoamine oxidase A for positron emission tomography imaging.

KW - Baboon

KW - Dosimetry

KW - Monoamine oxidase-A

KW - Positron emission tomography

UR - https://www.scopus.com/pages/publications/34547650869

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Biodistribution and radiation dosimetry of C-harmine in baboons

Abstract

Keywords

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