@inproceedings{3a3a223db1ab452287ae24d300495080,
title = "Biomarker detection by enzymatic amplification in droplets - Towards high throughput detection of low copy number cell surface biomarkers",
abstract = "We report the development of a microfluidic droplet-based assay for detecting very low numbers of surface biomarkers on single cells. The method hinges on an enzymatic amplification whose product is confined in each droplet. The device generates droplets [1] containing individual cells for analysis at rates up to 106 cells per hour. The CD45 biomarker on the cell surface of human T lymphocytes is used as a model system for the assay.",
keywords = "Antibodies, Cell Surface Biomarkers, Droplets, Enzymes",
author = "Joensson, \{Haakan N.\} and Brouzes, \{Eric R.\} and Michael Samuels and Mathias Uhl{\'e}n and Svahn, \{Helene Andersson\} and Link, \{Darren R.\}",
note = "Publisher Copyright: {\textcopyright} 2007 CBMS.; 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",
year = "2007",
language = "English",
series = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
publisher = "Chemical and Biological Microsystems Society",
pages = "113--115",
editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",
booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
}