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Bladder cancer diagnosis with fluorescence-image-guided optical coherence tomography

  • Stony Brook University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A fluorescence-image-guided OCT (FIG-OCT) system is described, and its ability to enhance the sensitivity and specificity is examined in an animal bladder cancer model. Total 97 specimens were examined by fluorescence imaging, OCT and histological microscopy. The sensitivity and specificity of FIG-OCT is 100% and 93% respectively, compared to 79% and 53% for fluorescence imaging, while the OCT examination time has been dramatically decreased by 3-4 times. In combination of endoscopic OCT, FIG-OCT is a promising technique for effective early bladder cancer diagnosis.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
DOIs
StatePublished - 2006
EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X - San Jose, CA, United States
Duration: Jan 23 2006Jan 25 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6079
ISSN (Print)0277-786X

Conference

ConferenceCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
Country/TerritoryUnited States
CitySan Jose, CA
Period01/23/0601/25/06

Keywords

  • 5-ALA fluorescence
  • Early bladder cancer diagnosis
  • Optical coherence tomography

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