TY - GEN
T1 - Burn monitoring using SFDI in a porcine model
AU - Kluiszo, Elias
AU - Belcastro, Luigi
AU - Ahmmed, Rasel
AU - Singer, Adam
AU - Clark, Richard
AU - Rafailovich, Miriam
AU - Sunar, Ulas
N1 - Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2026/3/4
Y1 - 2026/3/4
N2 - Current clinical burn assessment relies primarily on visual inspection, a method that often lacks precision in determining wound depth and severity during early stages. This study presents a portable, endoscopic Spatial Frequency Domain Imaging (SFDI) system designed to assess the absorption (μa) and reduced scattering (μs′) properties of biological tissue. While SFDI for burn assessment has historically been limited to widefield systems, our endoscopic application demonstrates improved mobility and ergonomics at the bedside. Using a porcine model, we quantified tissue responses to full-thickness thermal burns and liquid nitrogen-induced frostbite. Our findings reveal that these quantitative parameters provide objective insight into the hemodynamic and structural properties of wounds, offering a robust framework for determining injury severity and informing therapeutic strategies.
AB - Current clinical burn assessment relies primarily on visual inspection, a method that often lacks precision in determining wound depth and severity during early stages. This study presents a portable, endoscopic Spatial Frequency Domain Imaging (SFDI) system designed to assess the absorption (μa) and reduced scattering (μs′) properties of biological tissue. While SFDI for burn assessment has historically been limited to widefield systems, our endoscopic application demonstrates improved mobility and ergonomics at the bedside. Using a porcine model, we quantified tissue responses to full-thickness thermal burns and liquid nitrogen-induced frostbite. Our findings reveal that these quantitative parameters provide objective insight into the hemodynamic and structural properties of wounds, offering a robust framework for determining injury severity and informing therapeutic strategies.
UR - https://www.scopus.com/pages/publications/105035162294
U2 - 10.1117/12.3081368
DO - 10.1117/12.3081368
M3 - Conference contribution
AN - SCOPUS:105035162294
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photonics in Dermatology and Plastic Surgery 2026
A2 - Zeng, Haishan
A2 - Rajadhyaksha, Milind
PB - SPIE
T2 - Photonics in Dermatology and Plastic Surgery 2026
Y2 - 17 January 2026 through 19 January 2026
ER -