Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging

Daniel J. Rohrbach; Nathalie C. Zeitouni; Daniel Muffoletto; Rolf Saager; Bruce J. Tromberg; Ulas Sunar

doi:10.1364/BOE.6.001761

Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging

Daniel J. Rohrbach
, Nathalie C. Zeitouni
, Daniel Muffoletto
, Rolf Saager
, Bruce J. Tromberg
, Ulas Sunar

Roswell Park Cancer Institute
University of Arizona
SUNY Buffalo
University of California at Irvine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We utilized spatial frequency domain imaging to quantify optical and vascular parameters, as well as estimated light penetration depth from 17 nonmelanoma skin cancer patients. Our data indicates that there exist substantial spatial variations in these parameters. Characterization of these parameters may inform understanding and optimization of the clinical response of light-based therapies.

Original language	English
Article number	A016
Pages (from-to)	1761-1766
Number of pages	6
Journal	Biomedical Optics Express
Volume	6
Issue number	5
DOIs	https://doi.org/10.1364/BOE.6.001761
State	Published - Apr 20 2015

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10.1364/BOE.6.001761

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title = "Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging",

abstract = "The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We utilized spatial frequency domain imaging to quantify optical and vascular parameters, as well as estimated light penetration depth from 17 nonmelanoma skin cancer patients. Our data indicates that there exist substantial spatial variations in these parameters. Characterization of these parameters may inform understanding and optimization of the clinical response of light-based therapies.",

author = "Rohrbach, \{Daniel J.\} and Zeitouni, \{Nathalie C.\} and Daniel Muffoletto and Rolf Saager and Tromberg, \{Bruce J.\} and Ulas Sunar",

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AU - Rohrbach, Daniel J.

AU - Zeitouni, Nathalie C.

AU - Muffoletto, Daniel

AU - Saager, Rolf

AU - Tromberg, Bruce J.

AU - Sunar, Ulas

PY - 2015/4/20

Y1 - 2015/4/20

N2 - The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We utilized spatial frequency domain imaging to quantify optical and vascular parameters, as well as estimated light penetration depth from 17 nonmelanoma skin cancer patients. Our data indicates that there exist substantial spatial variations in these parameters. Characterization of these parameters may inform understanding and optimization of the clinical response of light-based therapies.

AB - The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We utilized spatial frequency domain imaging to quantify optical and vascular parameters, as well as estimated light penetration depth from 17 nonmelanoma skin cancer patients. Our data indicates that there exist substantial spatial variations in these parameters. Characterization of these parameters may inform understanding and optimization of the clinical response of light-based therapies.

UR - https://www.scopus.com/pages/publications/84948749050

U2 - 10.1364/BOE.6.001761

DO - 10.1364/BOE.6.001761

M3 - Article

AN - SCOPUS:84948749050

SN - 2156-7085

VL - 6

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EP - 1766

JO - Biomedical Optics Express

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IS - 5

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ER -

Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging

Abstract

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