Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs

Ann Schluederberg; Surina Chavanich; Muriel B. Lipman; Carol Carter

doi:10.1016/S0006-291X(74)80467-5

Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs

Ann Schluederberg
, Surina Chavanich
, Muriel B. Lipman
, Carol Carter

Microbiology and Immunology

Yale University

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Structural polypeptides of a measles virus strain isolated from a case of subacute sclerosing panencephalitis (SSPE) were compared with those of the Edmonston strain by electrophoresis in acrylamide gel slabs containing sodium dodecyl sulfate. The smallest polypeptide, which appears to be the membrane protein, of the SSPE strain migrated more slowly than the corresponding measles polypeptide, indicating molecular weights of 40,000 and 38,000 daltons, respectively. The five other proteins successfully compared showed identical mobilities. A greater concentration of one of these (66,000 daltons) was seen in SSPE virions.

Original language	English
Pages (from-to)	647-651
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/S0006-291X(74)80467-5
State	Published - Jun 4 1974

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10.1016/S0006-291X(74)80467-5

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title = "Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs",

abstract = "Structural polypeptides of a measles virus strain isolated from a case of subacute sclerosing panencephalitis (SSPE) were compared with those of the Edmonston strain by electrophoresis in acrylamide gel slabs containing sodium dodecyl sulfate. The smallest polypeptide, which appears to be the membrane protein, of the SSPE strain migrated more slowly than the corresponding measles polypeptide, indicating molecular weights of 40,000 and 38,000 daltons, respectively. The five other proteins successfully compared showed identical mobilities. A greater concentration of one of these (66,000 daltons) was seen in SSPE virions.",

author = "Ann Schluederberg and Surina Chavanich and Lipman, \{Muriel B.\} and Carol Carter",

year = "1974",

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doi = "10.1016/S0006-291X(74)80467-5",

language = "English",

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pages = "647--651",

journal = "Biochemical and Biophysical Research Communications",

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Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs. / Schluederberg, Ann; Chavanich, Surina; Lipman, Muriel B. et al.
In: Biochemical and Biophysical Research Communications, Vol. 58, No. 3, 04.06.1974, p. 647-651.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs

AU - Schluederberg, Ann

AU - Chavanich, Surina

AU - Lipman, Muriel B.

AU - Carter, Carol

PY - 1974/6/4

Y1 - 1974/6/4

N2 - Structural polypeptides of a measles virus strain isolated from a case of subacute sclerosing panencephalitis (SSPE) were compared with those of the Edmonston strain by electrophoresis in acrylamide gel slabs containing sodium dodecyl sulfate. The smallest polypeptide, which appears to be the membrane protein, of the SSPE strain migrated more slowly than the corresponding measles polypeptide, indicating molecular weights of 40,000 and 38,000 daltons, respectively. The five other proteins successfully compared showed identical mobilities. A greater concentration of one of these (66,000 daltons) was seen in SSPE virions.

AB - Structural polypeptides of a measles virus strain isolated from a case of subacute sclerosing panencephalitis (SSPE) were compared with those of the Edmonston strain by electrophoresis in acrylamide gel slabs containing sodium dodecyl sulfate. The smallest polypeptide, which appears to be the membrane protein, of the SSPE strain migrated more slowly than the corresponding measles polypeptide, indicating molecular weights of 40,000 and 38,000 daltons, respectively. The five other proteins successfully compared showed identical mobilities. A greater concentration of one of these (66,000 daltons) was seen in SSPE virions.

UR - https://www.scopus.com/pages/publications/0016190067

U2 - 10.1016/S0006-291X(74)80467-5

DO - 10.1016/S0006-291X(74)80467-5

M3 - Article

C2 - 4836268

AN - SCOPUS:0016190067

SN - 0006-291X

VL - 58

SP - 647

EP - 651

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 3

ER -

Comparative molecular weight estimates of measles and subacute sclerosing panencephalitis virus structural polypeptides by simultaneous electrophoresis in acrylamide gel slabs

Abstract

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