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Computational studies of copolymer adsorption at bilayer interfaces

  • University of Pittsburgh

Research output: Contribution to journalConference articlepeer-review

Abstract

The interactions between copolymers and bilayers play a crucial role in a variety of processes. For example, the interactions between proteins and lipid bilayers facilitate the transport of ions through the cell membranes. In addition, polymers the weave through the bilayers within the lamellar domains of microphase-separated diblocks enhance the adhesion between the layers. Consequently, by isolating the factors that govern chain-bilayer interactions, we can optimize the properties of polymeric materials or unravel the behavior of macromolecules at biological interfaces. In order to carry out these investigations, we developed a Monte Carlo simulation to model the interaction between an amphiphilic copolymer and a hydrophobic bilayer. We describe our computer model and summarize our recent results.

Original languageEnglish
Pages (from-to)57-58
Number of pages2
JournalPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
Volume69
StatePublished - 1993
EventProceedings of the American Chemical Society Division of Polymeric Materials - Science and Engineering - Chicago, IL, USA
Duration: Jun 11 1993Jun 11 1993

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