@inproceedings{5d1825fc3a704109948f867fcf4ef019,
title = "COMSOL Modeling of ISFET for pH Sensing and Antigen-Antibody Detection",
abstract = "This paper describes the development and validation of a comprehensive COMSOL Multiphysics {\textregistered} simulation model for Ion-Sensitive Field Effect Transistors (ISFETs) used for pH sensing. The model accurately captures the performance of fabricated ISFETs in measuring multiple pH electrolytes and also enables exploration of different sensing membrane materials and their thicknesses and impact on device sensitivity. The study validates the accuracy of the simulation model through laboratory experiments using a commercial ISFET with a Si3N4 layer as the sensing membrane. Based on the optimized ISFET model, the study further extends its scope to develop a simulation model for antigen-antibody detection, enabling the development of point-of-care devices.",
keywords = "COMSOL Multiphysics, DNA detection, ISFET, pH sensing, sensitivity, simulation methodology, surface functionalization",
author = "Utku Noyan and Glenn Ray and Cobb, \{Avery Snow\} and Pamela Abshire and Sahil Shah",
note = "Publisher Copyright: {\textcopyright} 2023 IEEE.; 2023 IEEE 66th International Midwest Symposium on Circuits and Systems, MWSCAS 2023 ; Conference date: 06-08-2023 Through 09-08-2023",
year = "2023",
doi = "10.1109/MWSCAS57524.2023.10405933",
language = "English",
series = "Midwest Symposium on Circuits and Systems",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "773--777",
booktitle = "2023 IEEE 66th International Midwest Symposium on Circuits and Systems, MWSCAS 2023",
}