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Continuous LYSO-SSPM array based PET detectors for clinical and small volume imaging studies

  • Purushottam Dokhale
  • , Rob Robertson
  • , Cristopher Stapels
  • , James Cristian
  • , Madhuri Kaul
  • , Suleman Surti
  • , Joel Karp
  • , Paul Vaska
  • , Kanai Shah
  • Radiation Monitoring Devices, Inc.
  • University of Pennsylvania

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

We are developing a large area thick continuous LYSO-solid state photomultiplier (SSPM) array based PET detectors to exploit the potential applications in clinical and small volume imaging studies. The PET detector design for clinical applications consists of a 47×47×14 mm 3 slab of LYSO crystal sandwiched between two 8X8 element SSPM arrays with 5×5 mm2 elements. The detector module for higher resolution, small volume imaging studies consists of a thin sheet ∼5-10mm of LYSO scintillator sandwiched between two 12X12 element SSPM arrays with 1.5×1.5 mm2 elements. Towards addressing this goal, here we present the construction and evaluation of 8X8 element SSPM array with each element being 5mm X 5mm in size. The SSPM array with an imaging area of 47×47 mm2 was created by close-tiling RMD's 2X2 array of 5×5 mm2 SSPM chips in a 4X4 format. Pixel uniformity, energy resolution and timing resolution for individual pixels in the 8X8 array was studied by coupling a single LYSO crystal measuring 3×3×15 mm 3 to each SSPM pixel in the array. The measured photopeak amplitude for 511 keV gamma-rays varied from 66 to 100 over the array. The energy resolution for all pixels in the array ranged from 10% to 12.5% (FWHM). The measured timing resolution for all pixels was in 700ps to 800ps range. Continuous crystal based PET module was also built by coupling a 47×47×8 mm3 slab of polished LYSO crystal to the 8X8 SSPM array. The energy resolution measured in the center of the crystal was 16.4% (FWHM) and at the edge it was 16.8% (FWHM). The coincidence timing resolution measured against LYSO-PMT detector was 1.1ns in the center and 1.3ns at the edge of the crystal. We also discuss the performance of a monolithic 6X6 SSPM array with each element 1.5mm X 1.5mm for smaller volume, higher resolution PET detectors. The energy resolution for all pixels in the array ranged from 13% to 15%. The measured timing resolution for all pixels was in the range of 500ps to 550ps.

Original languageEnglish
Title of host publication2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2350-2354
Number of pages5
ISBN (Print)9781467301183
DOIs
StatePublished - 2011
Event2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011 - Valencia, Spain
Duration: Oct 23 2011Oct 29 2011

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Country/TerritorySpain
CityValencia
Period10/23/1110/29/11

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