Design of a proton computed tomography system for applications in proton radiation therapy

Reinhard Schulte; Vladimir Bashkirov; Tianfang Li; Jerome Z. Liang; Klaus Mueller; Jason Heimann; Leah R. Johnson; Brian Keeney; Hartmut F.W. Sadrozinski; Abraham Seiden; David C. Williams; Lan Zhang; Zheng Li; Steven Peggs; Todd Satogata; Craig Woody

Design of a proton computed tomography system for applications in proton radiation therapy

Reinhard Schulte
, Vladimir Bashkirov
, Tianfang Li
, Jerome Z. Liang
, Klaus Mueller
, Jason Heimann
, Leah R. Johnson
, Brian Keeney
, Hartmut F.W. Sadrozinski
, Abraham Seiden
, David C. Williams
, Lan Zhang
, Zheng Li
, Steven Peggs
, Todd Satogata
, Craig Woody

Loma Linda University Health
Stony Brook University
University of California at Santa Cruz
Brookhaven National Laboratory

Research output: Contribution to journal › Conference article › peer-review

5 Scopus citations

Abstract

Proton computed tomography (pCT) has the potential to improve the accuracy of dose calculations for proton treatment planning, and will also be useful for pretreatment verification of patient positioning relative to the proton beam. A design study was performed to define the optimal approach to a pCT system based on specifications for applications in proton therapy. Conceptual and detailed design of a pCT system is presented consisting of a silicon-based particle tracking system and a crystal calorimeter to measure energy loss of individual protons. We discuss the formation of pCT images based on the reconstruction of volume electron density maps and the suitability of analytic and statistical algorithms for image reconstruction.

Original language	English
Article number	N41-2
Pages (from-to)	1579-1583
Number of pages	5
Journal	IEEE Nuclear Science Symposium Conference Record
Volume	3
State	Published - 2003
Event	2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States Duration: Oct 19 2003 → Oct 25 2003

Cite this

Schulte, R., Bashkirov, V., Li, T., Liang, J. Z., Mueller, K., Heimann, J., Johnson, L. R., Keeney, B., Sadrozinski, H. F. W., Seiden, A., Williams, D. C., Zhang, L., Li, Z., Peggs, S., Satogata, T., & Woody, C. (2003). Design of a proton computed tomography system for applications in proton radiation therapy. IEEE Nuclear Science Symposium Conference Record, 3, 1579-1583. Article N41-2.

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title = "Design of a proton computed tomography system for applications in proton radiation therapy",

abstract = "Proton computed tomography (pCT) has the potential to improve the accuracy of dose calculations for proton treatment planning, and will also be useful for pretreatment verification of patient positioning relative to the proton beam. A design study was performed to define the optimal approach to a pCT system based on specifications for applications in proton therapy. Conceptual and detailed design of a pCT system is presented consisting of a silicon-based particle tracking system and a crystal calorimeter to measure energy loss of individual protons. We discuss the formation of pCT images based on the reconstruction of volume electron density maps and the suitability of analytic and statistical algorithms for image reconstruction.",

author = "Reinhard Schulte and Vladimir Bashkirov and Tianfang Li and Liang, \{Jerome Z.\} and Klaus Mueller and Jason Heimann and Johnson, \{Leah R.\} and Brian Keeney and Sadrozinski, \{Hartmut F.W.\} and Abraham Seiden and Williams, \{David C.\} and Lan Zhang and Zheng Li and Steven Peggs and Todd Satogata and Craig Woody",

year = "2003",

language = "English",

volume = "3",

pages = "1579--1583",

journal = "IEEE Nuclear Science Symposium Conference Record",

issn = "1095-7863",

note = "2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference ; Conference date: 19-10-2003 Through 25-10-2003",

}

TY - JOUR

T1 - Design of a proton computed tomography system for applications in proton radiation therapy

AU - Schulte, Reinhard

AU - Bashkirov, Vladimir

AU - Li, Tianfang

AU - Liang, Jerome Z.

AU - Mueller, Klaus

AU - Heimann, Jason

AU - Johnson, Leah R.

AU - Keeney, Brian

AU - Sadrozinski, Hartmut F.W.

AU - Seiden, Abraham

AU - Williams, David C.

AU - Zhang, Lan

AU - Li, Zheng

AU - Peggs, Steven

AU - Satogata, Todd

AU - Woody, Craig

PY - 2003

Y1 - 2003

N2 - Proton computed tomography (pCT) has the potential to improve the accuracy of dose calculations for proton treatment planning, and will also be useful for pretreatment verification of patient positioning relative to the proton beam. A design study was performed to define the optimal approach to a pCT system based on specifications for applications in proton therapy. Conceptual and detailed design of a pCT system is presented consisting of a silicon-based particle tracking system and a crystal calorimeter to measure energy loss of individual protons. We discuss the formation of pCT images based on the reconstruction of volume electron density maps and the suitability of analytic and statistical algorithms for image reconstruction.

AB - Proton computed tomography (pCT) has the potential to improve the accuracy of dose calculations for proton treatment planning, and will also be useful for pretreatment verification of patient positioning relative to the proton beam. A design study was performed to define the optimal approach to a pCT system based on specifications for applications in proton therapy. Conceptual and detailed design of a pCT system is presented consisting of a silicon-based particle tracking system and a crystal calorimeter to measure energy loss of individual protons. We discuss the formation of pCT images based on the reconstruction of volume electron density maps and the suitability of analytic and statistical algorithms for image reconstruction.

UR - https://www.scopus.com/pages/publications/19944426220

M3 - Conference article

AN - SCOPUS:19944426220

SN - 1095-7863

VL - 3

SP - 1579

EP - 1583

JO - IEEE Nuclear Science Symposium Conference Record

JF - IEEE Nuclear Science Symposium Conference Record

M1 - N41-2

T2 - 2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference

Y2 - 19 October 2003 through 25 October 2003

ER -

Design of a proton computed tomography system for applications in proton radiation therapy

Abstract

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