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Detection and visualization of surface-pockets to enable phenotyping studies

  • Kishore Mosaliganti
  • , Firdaus Janoos
  • , Richard Sharp
  • , Randall Ridgway
  • , Raghu Machiraju
  • , Kun Huang
  • , Pamela Wenzel
  • , Alain DeBruin
  • , Gustavo Leone
  • , Joel Saltz
  • Ohio State University

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

In this paper, we propose a technique for detecting pockets on a surface-of-interest. A sequence of propagating fronts converging to the target surface is used as the basis for inspection. We compute a correspondence function between the initial and the target surface. This leads to a natural definition of the local feature size measured as the evolution distance between mapped points. Surface pockets are then extracted as salient clusters embedded in the feature space. The level-set initialization also determines the scale-space of the extracted pockets. Results are presented on a case-study in which the focus is to chronicle the phenotyping differences in genetically modified mouse placenta. Our results are validated based on manually verified ground-truth.

Original languageEnglish
Pages (from-to)1283-1290
Number of pages8
JournalIEEE Transactions on Medical Imaging
Volume26
Issue number9
DOIs
StatePublished - Sep 2007

Keywords

  • Computational phenotyping
  • Level-sets
  • Surfacepockets

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