Abstract
Within the last decade, animal models of anesthetic neurotoxicity and related developmental disorders have raised concerns for comparable effects in children after exposure to general anesthesia in early infancy. Millions of children undergo surgery during their first 4 years of life worldwide. Delaying non-elective surgical procedures might put children at risk of disease progression including neurodevelopmental impairment. Moreover, controlled anesthetic exposure is difficult to accomplish. This chapter describes the developing brain and different aspects of anesthesia-induced neurotoxicity.
| Original language | English |
|---|---|
| Title of host publication | Fundamentals of Pediatric Neuroanesthesia |
| Publisher | Springer Nature |
| Pages | 679-692 |
| Number of pages | 14 |
| ISBN (Electronic) | 9789811633768 |
| ISBN (Print) | 9789811633751 |
| DOIs | |
| State | Published - Jan 1 2021 |
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