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Developing Brain and Anesthetic Neurotoxicity

  • Women’s Hospital

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Within the last decade, animal models of anesthetic neurotoxicity and related developmental disorders have raised concerns for comparable effects in children after exposure to general anesthesia in early infancy. Millions of children undergo surgery during their first 4 years of life worldwide. Delaying non-elective surgical procedures might put children at risk of disease progression including neurodevelopmental impairment. Moreover, controlled anesthetic exposure is difficult to accomplish. This chapter describes the developing brain and different aspects of anesthesia-induced neurotoxicity.

Original languageEnglish
Title of host publicationFundamentals of Pediatric Neuroanesthesia
PublisherSpringer Nature
Pages679-692
Number of pages14
ISBN (Electronic)9789811633768
ISBN (Print)9789811633751
DOIs
StatePublished - Jan 1 2021

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