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Development of an immunocompetent human skin tissue model using three dimensional (3D) freeform fabrication

  • Gurtej Singh
  • , Vivian Lee
  • , John P. Trasatti
  • , Seung Schik Yoo
  • , Guohao Dai
  • , Pankaj Karande
  • Rensselaer Polytechnic Institute
  • Harvard University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

We report on the development of a novel in vitro, multi-compartmental, three-dimensional, Human Skin Tissue Experimental Model (HISTEM) using three-dimensional free form fabrication (3DFFF). The availability of this model is expected to positively impact the development of transdermal vaccines and immunomodulators for infectious diseases and autoimmune disorders. Our studies demonstrate the biological and structural equivalence of HISTEM with ex vivo human skin.

Original languageEnglish
Title of host publication2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011
DOIs
StatePublished - 2011
Event37th Annual Northeast Bioengineering Conference, NEBEC 2011 - Troy, NY, United States
Duration: Apr 1 2011Apr 3 2011

Publication series

Name2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011

Conference

Conference37th Annual Northeast Bioengineering Conference, NEBEC 2011
Country/TerritoryUnited States
CityTroy, NY
Period04/1/1104/3/11

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