TY - GEN
T1 - Development of an immunocompetent human skin tissue model using three dimensional (3D) freeform fabrication
AU - Singh, Gurtej
AU - Lee, Vivian
AU - Trasatti, John P.
AU - Yoo, Seung Schik
AU - Dai, Guohao
AU - Karande, Pankaj
PY - 2011
Y1 - 2011
N2 - We report on the development of a novel in vitro, multi-compartmental, three-dimensional, Human Skin Tissue Experimental Model (HISTEM) using three-dimensional free form fabrication (3DFFF). The availability of this model is expected to positively impact the development of transdermal vaccines and immunomodulators for infectious diseases and autoimmune disorders. Our studies demonstrate the biological and structural equivalence of HISTEM with ex vivo human skin.
AB - We report on the development of a novel in vitro, multi-compartmental, three-dimensional, Human Skin Tissue Experimental Model (HISTEM) using three-dimensional free form fabrication (3DFFF). The availability of this model is expected to positively impact the development of transdermal vaccines and immunomodulators for infectious diseases and autoimmune disorders. Our studies demonstrate the biological and structural equivalence of HISTEM with ex vivo human skin.
UR - https://www.scopus.com/pages/publications/79958708422
U2 - 10.1109/NEBC.2011.5778579
DO - 10.1109/NEBC.2011.5778579
M3 - Conference contribution
AN - SCOPUS:79958708422
SN - 9781612848273
T3 - 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011
BT - 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011
T2 - 37th Annual Northeast Bioengineering Conference, NEBEC 2011
Y2 - 1 April 2011 through 3 April 2011
ER -