Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat

William F. Collins; Andrew W. Seymour; Sharon W. Klugewicz

doi:10.1016/0006-8993(92)90292-H

Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat

William F. Collins
, Andrew W. Seymour
, Sharon W. Klugewicz

Neurobiology and Behavior

Stony Brook University

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

We have examined the organization of the androgen sensitivity of pudendal motoneurons in adult male rats. Comparisons of mean somal cross sectional area of pudendal motoneurons identified by retrograde labeling with horseradish peroxidase were made between three treatment groups: castrates with testosterone propionate supplementation, castrates with placebo, and sham castrates. Bulbospongiosus and ischiocavernosus motoneurons were sensitive to androgen treatment, whereas external anal sphincter and external urethral sphincter motoneurons were not.

Original language	English
Pages (from-to)	326-330
Number of pages	5
Journal	Brain Research
Volume	577
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(92)90292-H
State	Published - Apr 17 1992

Keywords

Androgen
Penis
Sexual dimorphism
Sexual reflex
Spinal cord

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10.1016/0006-8993(92)90292-H

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title = "Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat",

abstract = "We have examined the organization of the androgen sensitivity of pudendal motoneurons in adult male rats. Comparisons of mean somal cross sectional area of pudendal motoneurons identified by retrograde labeling with horseradish peroxidase were made between three treatment groups: castrates with testosterone propionate supplementation, castrates with placebo, and sham castrates. Bulbospongiosus and ischiocavernosus motoneurons were sensitive to androgen treatment, whereas external anal sphincter and external urethral sphincter motoneurons were not.",

keywords = "Androgen, Penis, Sexual dimorphism, Sexual reflex, Spinal cord",

author = "Collins, \{William F.\} and Seymour, \{Andrew W.\} and Klugewicz, \{Sharon W.\}",

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T1 - Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat

AU - Collins, William F.

AU - Seymour, Andrew W.

AU - Klugewicz, Sharon W.

PY - 1992/4/17

Y1 - 1992/4/17

N2 - We have examined the organization of the androgen sensitivity of pudendal motoneurons in adult male rats. Comparisons of mean somal cross sectional area of pudendal motoneurons identified by retrograde labeling with horseradish peroxidase were made between three treatment groups: castrates with testosterone propionate supplementation, castrates with placebo, and sham castrates. Bulbospongiosus and ischiocavernosus motoneurons were sensitive to androgen treatment, whereas external anal sphincter and external urethral sphincter motoneurons were not.

AB - We have examined the organization of the androgen sensitivity of pudendal motoneurons in adult male rats. Comparisons of mean somal cross sectional area of pudendal motoneurons identified by retrograde labeling with horseradish peroxidase were made between three treatment groups: castrates with testosterone propionate supplementation, castrates with placebo, and sham castrates. Bulbospongiosus and ischiocavernosus motoneurons were sensitive to androgen treatment, whereas external anal sphincter and external urethral sphincter motoneurons were not.

KW - Androgen

KW - Penis

KW - Sexual dimorphism

KW - Sexual reflex

KW - Spinal cord

UR - https://www.scopus.com/pages/publications/0026598440

U2 - 10.1016/0006-8993(92)90292-H

DO - 10.1016/0006-8993(92)90292-H

M3 - Article

C2 - 1606503

AN - SCOPUS:0026598440

SN - 0006-8993

VL - 577

SP - 326

EP - 330

JO - Brain Research

JF - Brain Research

IS - 2

ER -

Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat

Abstract

Keywords

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