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Diffusion Transformer U-Net for Medical Image Segmentation

  • Stony Brook University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

44 Scopus citations

Abstract

Diffusion model has shown its power on various generation tasks. When applying the diffusion model in medical image segmentation, there are a few roadblocks to remove: the semantic features required for the conditioning of the diffusion process are not well aligned with the noise embedding; and the U-Net backbone employed in these diffusion models is not sensitive to contextual information that is essential during the reverse diffusion process for accurate pixel-level segmentation. To overcome these limitations, we present a cross-attention module to enhance the conditioning from source images, and a transformer based U-Net with multi-sized windows for the extraction of various scales of contextual information. Evaluated on five benchmark datasets with different imaging modalities including Kvasir-Seg, CVC Clinic DB, ISIC 2017, ISIC 2018, and Refuge, our diffusion transformer U-Net achieves great generalization ability and outperforms all the state-of-the-art models on these datasets.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2023 - 26th International Conference, Proceedings
EditorsHayit Greenspan, Hayit Greenspan, Anant Madabhushi, Parvin Mousavi, Septimiu Salcudean, James Duncan, Tanveer Syeda-Mahmood, Russell Taylor
PublisherSpringer Science and Business Media Deutschland GmbH
Pages622-631
Number of pages10
ISBN (Print)9783031439001
DOIs
StatePublished - 2023
Event26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023 - Vancouver, Canada
Duration: Oct 8 2023Oct 12 2023

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume14223 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023
Country/TerritoryCanada
CityVancouver
Period10/8/2310/12/23

Keywords

  • Diffusion model
  • Medical Image Segmentation
  • Transformer
  • U-Net

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