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Digital coincidence processing for the RatCAP conscious rat brain PET scanner

  • S. J. Park
  • , S. Southekal
  • , M. Purschke
  • , S. S. Junnarkar
  • , J. F. Pratte
  • , V. Radeka
  • , P. O'Connor
  • , S. P. Stoll
  • , R. Lecomte
  • , R. Fontaine
  • , C. L. Woody
  • , D. J. Schlyer
  • , P. Vaska
  • Brookhaven National Laboratory
  • Stony Brook University
  • Université de Sherbrooke

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

The RatCAP has been designed and constructed to image the awake rat brain. In order to maximize system performance, offline digital coincidence data processing algorithms including offset delay correction and prompt and delayed coincidence detection have been developed and validated. With offset delay correction using a singular value decomposition (SVD) technique, overall time resolution was improved from 32.6 ns to 17.6 ns FWHM. The experimental results confirm that the ratio of prompts (or trues) to randoms was improved because a smaller timing window could be used. 18F-fluoride rat bone scan data was reconstructed with our fully 3-D MLEM with a highly accurate detector response model using Monte Carlo simulation.

Original languageEnglish
Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages3045-3048
Number of pages4
ISBN (Print)1424405610, 9781424405619
DOIs
StatePublished - 2006
Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
Duration: Oct 29 2006Nov 4 2006

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume5
ISSN (Print)1095-7863

Conference

Conference2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
Country/TerritoryUnited States
CitySan Diego, CA
Period10/29/0611/4/06

Keywords

  • Awake rat
  • Offset delay correction
  • RatCAP
  • Singular value decomposition (SVD)

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