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DNA migration and separation on surfaces with a microscale dielectrophoretic trap array

  • Harvard University
  • Stony Brook University
  • Columbia University

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.

Original languageEnglish
Article number088102
JournalPhysical Review Letters
Volume98
Issue number8
DOIs
StatePublished - Feb 20 2007

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