Driving forces in the origins of life

K. A. Dill; L. Agozzino

doi:10.1098/rsob.200324

Driving forces in the origins of life

K. A. Dill
, L. Agozzino

Laufer Center for Physical and Quantitative Biology

Stony Brook University

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic 'discoveries': persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a 'proteins-first' world gives plausible mechanisms. We note the importance of hydrophobic and polar compositions of matter in these advances.

Original language	English
Article number	200324
Journal	Open Biology
Volume	11
Issue number	2
DOIs	https://doi.org/10.1098/rsob.200324
State	Published - Feb 2 2021

Keywords

autocatalysis
fitness
origin of life
survival of the fittest

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KW - origin of life

KW - survival of the fittest

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Driving forces in the origins of life

Abstract

Keywords

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