Early identification and interventions for autism spectrum disorder: Executive summary

Lonnie Zwaigenbaum; Margaret L. Bauman; Roula Choueiri; Deborah Fein; Connie Kasari; Karen Pierce; Wendy L. Stone; Nurit Yirmiya; Annette Estes; Robin L. Hansen; James C. McPartland; Marvin R. Natowicz; Timothy Buie; Alice Carter; Patricia A. Davis; Doreen Granpeesheh; Zoe Mailloux; Craig Newschaffer; Diana Robins; Susanne Smith Roley; Sheldon Wagner; Amy Wetherby

doi:10.1542/peds.2014-3667B

Early identification and interventions for autism spectrum disorder: Executive summary

Lonnie Zwaigenbaum
, Margaret L. Bauman
, Roula Choueiri
, Deborah Fein
, Connie Kasari
, Karen Pierce
, Wendy L. Stone
, Nurit Yirmiya
, Annette Estes
, Robin L. Hansen
, James C. McPartland
, Marvin R. Natowicz
, Timothy Buie
, Alice Carter
, Patricia A. Davis
, Doreen Granpeesheh
, Zoe Mailloux
, Craig Newschaffer
, Diana Robins
, Susanne Smith Roley

Sheldon Wagner, Amy Wetherby

Pediatrics

University of Alberta
Boston University
University of Connecticut
University of California at Los Angeles
University of California at San Diego
University of Washington
Hebrew University of Jerusalem
University of California at Davis
Yale University
Cleveland Clinic Foundation
Harvard University
University of Massachusetts Boston
Integrated Center for Child Development
Center for Autism and Related Disorders
Thomas Jefferson University
Drexel University
University of Southern California
Behavioral Development and Educational Services
Florida State University

Research output: Contribution to journal › Article › peer-review

127 Scopus citations

Abstract

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10% to 19%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.

Original language	English
Pages (from-to)	S1-S9
Journal	Pediatrics
Volume	136
DOIs	https://doi.org/10.1542/peds.2014-3667B
State	Published - Oct 1 2015

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Zwaigenbaum, L., Bauman, M. L., Choueiri, R., Fein, D., Kasari, C., Pierce, K., Stone, W. L., Yirmiya, N., Estes, A., Hansen, R. L., McPartland, J. C., Natowicz, M. R., Buie, T., Carter, A., Davis, P. A., Granpeesheh, D., Mailloux, Z., Newschaffer, C., Robins, D., ... Wetherby, A. (2015). Early identification and interventions for autism spectrum disorder: Executive summary. Pediatrics, 136, S1-S9. https://doi.org/10.1542/peds.2014-3667B

@article{843b32eaa9164c10832272b48776d3db,

title = "Early identification and interventions for autism spectrum disorder: Executive summary",

abstract = "Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10\% to 19\%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.",

author = "Lonnie Zwaigenbaum and Bauman, \{Margaret L.\} and Roula Choueiri and Deborah Fein and Connie Kasari and Karen Pierce and Stone, \{Wendy L.\} and Nurit Yirmiya and Annette Estes and Hansen, \{Robin L.\} and McPartland, \{James C.\} and Natowicz, \{Marvin R.\} and Timothy Buie and Alice Carter and Davis, \{Patricia A.\} and Doreen Granpeesheh and Zoe Mailloux and Craig Newschaffer and Diana Robins and Roley, \{Susanne Smith\} and Sheldon Wagner and Amy Wetherby",

note = "Publisher Copyright: Copyright {\textcopyright} 2015 by the American Academy of Pediatrics.",

year = "2015",

month = oct,

day = "1",

doi = "10.1542/peds.2014-3667B",

language = "English",

volume = "136",

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journal = "Pediatrics",

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}

Zwaigenbaum, L, Bauman, ML, Choueiri, R, Fein, D, Kasari, C, Pierce, K, Stone, WL, Yirmiya, N, Estes, A, Hansen, RL, McPartland, JC, Natowicz, MR, Buie, T, Carter, A, Davis, PA, Granpeesheh, D, Mailloux, Z, Newschaffer, C, Robins, D, Roley, SS, Wagner, S & Wetherby, A 2015, 'Early identification and interventions for autism spectrum disorder: Executive summary', Pediatrics, vol. 136, pp. S1-S9. https://doi.org/10.1542/peds.2014-3667B

TY - JOUR

T1 - Early identification and interventions for autism spectrum disorder

T2 - Executive summary

AU - Zwaigenbaum, Lonnie

AU - Bauman, Margaret L.

AU - Choueiri, Roula

AU - Fein, Deborah

AU - Kasari, Connie

AU - Pierce, Karen

AU - Stone, Wendy L.

AU - Yirmiya, Nurit

AU - Estes, Annette

AU - Hansen, Robin L.

AU - McPartland, James C.

AU - Natowicz, Marvin R.

AU - Buie, Timothy

AU - Carter, Alice

AU - Davis, Patricia A.

AU - Granpeesheh, Doreen

AU - Mailloux, Zoe

AU - Newschaffer, Craig

AU - Robins, Diana

AU - Roley, Susanne Smith

AU - Wagner, Sheldon

AU - Wetherby, Amy

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10% to 19%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.

AB - Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10% to 19%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.

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DO - 10.1542/peds.2014-3667B

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AN - SCOPUS:84942932871

SN - 0031-4005

VL - 136

SP - S1-S9

JO - Pediatrics

JF - Pediatrics

ER -

Early identification and interventions for autism spectrum disorder: Executive summary

Abstract

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