Skip to main navigation Skip to search Skip to main content

Enhancement of Vaginal Infection in Mice by Herpes Simplex Virus Type II with Progesterone

  • University of Pennsylvania

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Nonpregnant, pregnant and progesterone treated mice were infected intravaginally with HSV II. Mortality rates were 10%, 88% and 88% respectively. Progesterone levels were 80–100 times greater in the treated mice and 10–70 times greater in the pregnant mice than controls. We were able to simulate the increased susceptibility of pregnant mice by administration of progesterone to nonpregnant female mice.

Original languageEnglish
Pages (from-to)131-134
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume158
Issue number2
DOIs
StatePublished - Jun 1978

Fingerprint

Dive into the research topics of 'Enhancement of Vaginal Infection in Mice by Herpes Simplex Virus Type II with Progesterone'. Together they form a unique fingerprint.

Cite this