Experimental study of the formation of high-resistivity zones at the gel/buffer interface in CE

Vyacheslav Khozikov; Olga Kosobokova; Gregory Citver; George Tyshko; Dmitri N. Gavrilov; George Gudkov; Vera Gorfinkel

doi:10.1002/elps.200500599

Experimental study of the formation of high-resistivity zones at the gel/buffer interface in CE

Vyacheslav Khozikov
, Olga Kosobokova
, Gregory Citver
, George Tyshko
, Dmitri N. Gavrilov
, George Gudkov
, Vera Gorfinkel

Electrical Engineering

Mayo Clinic Rochester, MN
Stony Brook University

Research output: Contribution to journal › Article › peer-review

Abstract

A novel, nondamaging method for experimental characterization of the formation and propagation of high-resistivity zones in CE, based on the measurement of time-dependent Joule heating on the outer capillary surface is proposed. The method detects propagation of resistive regions in capillaries in real time and allows the estimation of their velocity and resistance. The presented experimental data are in agreement with the results of the computer simulation as well as with previous data on the subject. The proposed method is useful for the development of new polymers as well as for the refinement and optimization of new CE protocols.

Original language	English
Pages (from-to)	317-321
Number of pages	5
Journal	Electrophoresis
Volume	28
Issue number	3
DOIs	https://doi.org/10.1002/elps.200500599
State	Published - Feb 2007

Keywords

CE
High-resistivity zone
Joule heating

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10.1002/elps.200500599

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title = "Experimental study of the formation of high-resistivity zones at the gel/buffer interface in CE",

abstract = "A novel, nondamaging method for experimental characterization of the formation and propagation of high-resistivity zones in CE, based on the measurement of time-dependent Joule heating on the outer capillary surface is proposed. The method detects propagation of resistive regions in capillaries in real time and allows the estimation of their velocity and resistance. The presented experimental data are in agreement with the results of the computer simulation as well as with previous data on the subject. The proposed method is useful for the development of new polymers as well as for the refinement and optimization of new CE protocols.",

keywords = "CE, High-resistivity zone, Joule heating",

author = "Vyacheslav Khozikov and Olga Kosobokova and Gregory Citver and George Tyshko and Gavrilov, \{Dmitri N.\} and George Gudkov and Vera Gorfinkel",

year = "2007",

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T1 - Experimental study of the formation of high-resistivity zones at the gel/buffer interface in CE

AU - Khozikov, Vyacheslav

AU - Kosobokova, Olga

AU - Citver, Gregory

AU - Tyshko, George

AU - Gavrilov, Dmitri N.

AU - Gudkov, George

AU - Gorfinkel, Vera

PY - 2007/2

Y1 - 2007/2

N2 - A novel, nondamaging method for experimental characterization of the formation and propagation of high-resistivity zones in CE, based on the measurement of time-dependent Joule heating on the outer capillary surface is proposed. The method detects propagation of resistive regions in capillaries in real time and allows the estimation of their velocity and resistance. The presented experimental data are in agreement with the results of the computer simulation as well as with previous data on the subject. The proposed method is useful for the development of new polymers as well as for the refinement and optimization of new CE protocols.

AB - A novel, nondamaging method for experimental characterization of the formation and propagation of high-resistivity zones in CE, based on the measurement of time-dependent Joule heating on the outer capillary surface is proposed. The method detects propagation of resistive regions in capillaries in real time and allows the estimation of their velocity and resistance. The presented experimental data are in agreement with the results of the computer simulation as well as with previous data on the subject. The proposed method is useful for the development of new polymers as well as for the refinement and optimization of new CE protocols.

KW - CE

KW - High-resistivity zone

KW - Joule heating

UR - https://www.scopus.com/pages/publications/33846987200

U2 - 10.1002/elps.200500599

DO - 10.1002/elps.200500599

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AN - SCOPUS:33846987200

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SP - 317

EP - 321

JO - Electrophoresis

JF - Electrophoresis

IS - 3

ER -

Experimental study of the formation of high-resistivity zones at the gel/buffer interface in CE

Abstract

Keywords

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