Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

Iwao Ojima; Tao Wang; Francette Delaloge

doi:10.1016/S0040-4039(98)00643-1

Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

Iwao Ojima
, Tao Wang
, Francette Delaloge

Chemistry

Stony Brook University

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.

Original language	English
Pages (from-to)	3663-3666
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	22
DOIs	https://doi.org/10.1016/S0040-4039(98)00643-1
State	Published - May 28 1998

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title = "Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids",

abstract = "New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.",

author = "Iwao Ojima and Tao Wang and Francette Delaloge",

year = "1998",

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doi = "10.1016/S0040-4039(98)00643-1",

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T1 - Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

AU - Ojima, Iwao

AU - Wang, Tao

AU - Delaloge, Francette

PY - 1998/5/28

Y1 - 1998/5/28

N2 - New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.

AB - New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.

UR - https://www.scopus.com/pages/publications/0032575139

U2 - 10.1016/S0040-4039(98)00643-1

DO - 10.1016/S0040-4039(98)00643-1

M3 - Article

AN - SCOPUS:0032575139

SN - 0040-4039

VL - 39

SP - 3663

EP - 3666

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 22

ER -

Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

Abstract

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