Facteurs de risque de toxoplasmose cérébrale chez les patients infectés par le VIH: données d'un essai de prophylaxie primaire

To identify risk factors for cerebral toxoplasmosis (CT) in HIV patients (pts) with positive serology for Toxoplasma gondii and CD4 < 200/mm³, data from the placebo group (N = 280) of a primary prophylaxis trial, were analyzed. The probability of onset of CT (n = 46) was, at one year, 13.1%. Three baseline variables were independently associated with a higher risk of CT: group IV non AIDS, AIDS stage and CD4 < 50/mm³. Initial titer of antibodies to Toxoplasma gondii was not.